| 益气活血温阳法治疗慢性心力衰竭疗效及对NT-proBNP、hs-CRP的影响 |
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| 引用本文： | 郭悦. 益气活血温阳法治疗慢性心力衰竭疗效及对NT-proBNP、hs-CRP的影响[J]. 心脏杂志, 2018, 30(2): 196-199 |
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| 作者姓名： | 郭悦 |
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| 作者单位： | 辽宁中医药大学附属医院心内科 |
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| 摘 要： | 目的 观察用益气温阳活血法治疗慢性心力衰竭(CHF)的临床疗效及对N末端脑钠尿肽前体（NT-proBNP）、超敏C反应蛋白（hs-CRP）的影响。方法 选择72例我科室收治的CHF患者,按随机数字法分为常规组（35例）和试药组（37例）,两组患者均根据病情给予西医常规治疗,试药组再加用自拟中药益气温阳活血复方。结果 试药组总有效率（89%）明显高于常规组（77%）（P<0.05）;治疗前两组左室舒张末期直径（LVEDD）、左室射血分数（LVEF）、舒张早期E峰流速与舒张晚期A峰流速的比值（E/A）、NT-proBNP、hs-CRP等差异均无统计学意义。治疗后两组均有改善,试药组显著优于常规组（P<0.05）。结论 在西医常规治疗的基础上加用益气温阳活血法治疗CHF效果显著优于单纯西医（常规）治疗。
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| 关 键 词： | 益气活血温阳 心力衰竭,慢性 N末端脑钠尿肽前体 超敏C反应蛋白 |
| 收稿时间： | 2017-02-23 |
Yiqi Huoxue Wenyang method for treatment of chronic heart failure and its influence on NT-proBNP and hs-CRP |
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| Abstract: | AIM To observe the clinical effect of the method of Yiqi Huoxue Wenyang (supplementing Qi and warming yang and promoting blood circulation) in the treatment of chronic heart failure and its effect on hs-CRP and NT-proBNP. METHODS Seventy-two patients with chronic heart failure in our hospital were divided into two groups using the method of random data points, e.g., routine group (35 cases) and treatment group (37 cases). Patients in both groups were given conventional Western medicine treatment according to their conditions, while the patients in the observation group were additionally given Yiqi Wenyang Huoxue Compound, a self-made traditional Chinese medicine. RESULTS Total efficiency in the observational group was significantly higher than that in the routine group (89% vs. 77%) and the difference was significant (P<0.05). Before treatment, no significant differences were found in LVEDD, LVEF and E/a value between the two groups. After treatment, the indexes were improved in both groups, but the improvement in the observational group was much better than that in the routine group (P<0.05). Before treatment, no significant difference was found in the values of hs-CRP and NT-pro BNP between the two groups. After treatment, both groups were both improved, but the improvement in the observational group was much better than that in the routine group (P<0.05). CONCLUSION The therapeutic effect of conventional treatment of Western medicine plus the method of Invigorating Qi and warming yang and promoting blood circulation is superior to Western medicine alone in the treatment of patients with chronic heart failure. |
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