| 婚姻状况对少突胶质细胞瘤患者预后的影响 |
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| 引用本文： | 于雪迪,佘春华,孙增峰,尹 强,纪昕欣,马 莉,李文良. 婚姻状况对少突胶质细胞瘤患者预后的影响[J]. 天津医科大学学报, 2019, 0(5): 488-492+495 |
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| 作者姓名： | 于雪迪 佘春华 孙增峰 尹 强 纪昕欣 马 莉 李文良 |
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| 作者单位： | （天津医科大学肿瘤医院脑系肿瘤科，国家肿瘤临床医学研究中心，天津市“肿瘤防治”重点实验室，天津市恶性肿瘤临床医学研究中心，天津300060） |
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| 摘 要： | 目的:探讨少突胶质细胞瘤患者婚姻状况与预后之间的关系。方法:纳入SEER数据库中自1973-2015年诊断为少突胶质细胞瘤的4 282例患者。通过Kaplan-Meier法分析患者生存率，Cox回归模型分析影响生存的独立危险因素。结果:单因素分析显示，性别、年龄、手术情况、原发灶部位、婚姻状况与少突胶质细胞瘤患者生存期相关（P<0.01）。多因素分析发现，婚姻状况是患者生存的独立预后因素（P<0.05），在相同性别、年龄范围、手术治疗情况下，丧偶仍是患者的独立危险因素（P<0.01）。结论:婚姻状况与少突胶质细胞瘤患者生存期密切相关，丧偶增加患者的死亡风险。
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| 关 键 词： | 少突胶质细胞瘤 婚姻状态 预后 SEER规划 |
Effects of marital status on patient prognosis in oligodendroglioma |
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| YU Xue-di,SHE Chun-hua,SUN Zeng-feng,YIN Qiang,JI Xin-xin,MA Li,LI Wen-liang. Effects of marital status on patient prognosis in oligodendroglioma[J]. Journal of Tianjin Medical University, 2019, 0(5): 488-492+495 |
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| Authors: | YU Xue-di SHE Chun-hua SUN Zeng-feng YIN Qiang JI Xin-xin MA Li LI Wen-liang |
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| Affiliation: | （Department of Brain Oncology, Cancer Institute and Hospital, Tianjin Medical University, National Clinical Research Center for Cancer,Key Laboratoryof Cancer Prevention and Therapy, Tianjin’s Clinical Research Center for Cancer, Tianjin 300060, China） |
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| Abstract: | Objective: To investigate the impact of marital status on patient prognosis in oligodendroglioma. Methods:We collected 4282 eligible patients with oligodendroglioma from SEER database from 1973 to 2015. Kaplan-Meier methods were used to analyze the patients’ survival, and Cox regression models were applied to analyze independent risk factors for patients’overall survival in oligodendroglioma. Results: Univariate analysis showedthat gender, age,surgery status, and primary siteandmarital status were significantly associated with patients’ overall survival in oligodendroglioma（P <0.01）. Multivariate analysis found that marital status wasthe independent prognostic factor for patients’ overall survival（P <0.05）. Widowed remained the independent risk factor for patients with the same gender, age range or surgery status（P<0.01）. Conclusion: Marital status might be closely associated with patients’ overall survival in oligodendroglioma, and widowed may increase the risk of death in patients. |
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| Keywords: | oligodendroglioma marital status prognosis SEER Program |
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