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宁波市江北区室外细颗粒物污染对儿科呼吸系统疾病的影响
引用本文:吴一峰,陆蓓蓓,陆毓剑,谷少华,王爱红,周逸夫,张霞红. 宁波市江北区室外细颗粒物污染对儿科呼吸系统疾病的影响[J]. 疾病监测, 2019, 34(3): 265-271. DOI: 10.3784/j.issn.1003-9961.2019.03.018
作者姓名:吴一峰  陆蓓蓓  陆毓剑  谷少华  王爱红  周逸夫  张霞红
作者单位:宁波市江北区疾病预防控制中心,浙江宁波,315020;宁波市疾病预防控制中心,浙江宁波,315010;宁波大学医学院附属医院医务科,浙江宁波,315020
基金项目:宁波市科技计划项目(No. 2016A610198);宁波市医学科技计划项目(No. 2016A02)
摘    要:目的探索室外细颗粒物(PM_(2.5))对浙江省宁波市江北区儿科门诊患者呼吸系统疾病日门诊量的影响。方法收集2014—2017年江北区各医院儿科门诊患者资料及同期污染物浓度和气象资料,采用分布滞后非线性模型计算相对危险度。结果 2014—2017年儿科门诊因呼吸系统疾病就诊984 941人次。PM_(2.5)浓度较低时对儿科呼吸系统疾病日门诊量增加的效应增长缓慢,而在较高浓度时,累积效应随着浓度的增加快速上升。同浓度PM_(2.5)的效应随着滞后天数的增加而减少。不同浓度PM_(2.5)的滞后天数不同,最长可滞后20 d。同一浓度PM_(2.5)对不同性别儿童的效应无差别,而对不同年龄儿童作用强度不同,3岁组和4~6岁组受到的效应最强。在滞后10 d以前,各浓度PM_(2.5)更易引起急性上呼吸道感染,但在10 d之后,对慢性下呼吸道疾病的效应更强,且后者的滞后天数更长。结论 PM_(2.5)浓度的升高会增加儿科呼吸系统疾病门诊就诊量,并存在滞后效应。同一浓度PM_(2.5)对不同年龄段儿童造成的危害有差别,但在性别方面没有差别,PM_(2.5)在早期更易引起急性上呼吸道感染,但对慢性下呼吸道疾病的效应更持久。

关 键 词:细颗粒物  呼吸系统疾病  儿科  分布滞后非线性模型
收稿时间:2018-03-29

Effects of outdoor air fine particle (PM2.5) pollution on respiratory diseases in children in Jiangbei district of Ningbo
Affiliation:1.Jiangbei District Center for Disease Control and Prevention, Ningbo 315020, Zhejiang, China2.Ningbo City Center for Disease Control and Prevention, Ningbo 315010, Zhejiang, China3.Affiliated Hospital of Medical College of Ningbo University, Ningbo 315020, Zhejiang, China
Abstract:ObjectiveTo evaluate the effect of outdoor air fine particle (PM2.5) on pediatric outpatient visits due to respiratory diseases in Jiangbei district of Ningbo.MethodsData of pediatric outpatient visits due to respiratory diseases in hospitals of Jiangbei district from 2014 to 2017 was collected, and the air pollution and meteorological data during the same period were collected too. The relative risk was calculated by using the distributed lag nonlinear model.ResultsA total of 984 941 pediatric outpatient visits due to respiratory diseases were recorded in Jiangbei district from 2014 to 2017. The effect of PM2.5 increased slowly at low concentration, but increased quickly at high concentration. The effect of PM2.5 at the same concentration decreased with the increase of lag days. The lag days of PM2.5 effects at different concentrations were different, and the longest could be 20 days. The effects of PM2.5 on boys and girls showed no difference, but the effects were different on age groups, the effects on 3 and 4–6 years old children were strongest. PM2.5 was more likely to cause acute upper respiratory tract infection before 10 lag days, but after 10 lag days, the effect on chronic lower respiratory diseases was stronger and longer.ConclusionThe rise of PM2.5 concentration would increase the pediatric outpatient visits due to respiratory diseases and has a lag effect. A PM2.5 concentration has different health hazards to children with different age, but there is no gender specific difference. PM2.5 is more likely to cause acute upper respiratory tract infection in early stage, but the effect on chronic lower respiratory tract disease is longer.
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