| 5-氨基酮戊酸光动力治疗基底细胞癌疗效评价 |
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| 引用本文： | 杨永华,裴晓燕,赵伟,刘鑫洲,单晓峰,田洪青. 5-氨基酮戊酸光动力治疗基底细胞癌疗效评价[J]. 中国麻风皮肤病杂志, 2021, 37(6): 365-368. DOI: 10.12144/zgmfskin202106365 |
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| 作者姓名： | 杨永华 裴晓燕 赵伟 刘鑫洲 单晓峰 田洪青 |
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| 作者单位： | 山东第一医科大学附属皮肤病医院（山东省皮肤病医院，山东省皮肤病性病防治研究所），济南，250022 |
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| 摘 要： | 目的:评价5-氨基酮戊酸光动力(ALA-PDT)治疗基底细胞癌的疗效及安全性.方法:回顾2016-2019年我院进行ALA-PDT治疗的17例基底细胞癌患者(浅表型14例,结节型3例)的临床资料.结果:14例浅表型基底细胞癌患者中13例患者皮损消退,仅留轻微色素沉着或色素减退,2例复发,1例于治疗后6个月后复发,1例于...
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| 关 键 词： | 光动力 基底细胞癌 |
Assessment the efficacy of 5-aminolevulinic acid mediated photodynamic therapy for the treatment of basal cell carcinoma |
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| YANG Yonghua,PEI Xiaoyan,ZHAO Wei,LIU Xinzhou,SHAN Xiaofeng,TIAN Hongqing. Assessment the efficacy of 5-aminolevulinic acid mediated photodynamic therapy for the treatment of basal cell carcinoma[J]. China Journal of Leprosy and Skin Diseases, 2021, 37(6): 365-368. DOI: 10.12144/zgmfskin202106365 |
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| Authors: | YANG Yonghua PEI Xiaoyan ZHAO Wei LIU Xinzhou SHAN Xiaofeng TIAN Hongqing |
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| Affiliation: | Shandong Provincial Hospital for Skin Diseases & Shandong Prouincial Institute of Dermatology and Veneorology, Shandong Fist Medical Univesity, Jinan 250022, China |
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| Abstract: | Objective: To assess the efficacy and safety of 5-aminolevulinic acid photodynamic therapy (ALA-PDT) in the treatment of basal cell carcinoma. Methods: The data of 17 patients with basal cell carcinoma（BCC）(including 14 cases of superficial BCC and 3 cases of nodular BCC) treated by ALA-PDT were analyzed retrospectively. Results: Of 14 patients with superficial BCC, the lesions in 13 cases were in complete remission with slight pigmentation or hypopigmentation left. Two of them recurred at month 6 and month 10 after treatment respectively. The size of the lesions in 3 patients with nodular BCC reduced by 50%. There was no obvious adverse reaction in all patients. Conclusion: ALA-PDT has good clinical effect and low recurrence rate for the treatment of superficial BCC. However, it has low efficacy for the treatment of nodular BCC. |
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| Keywords: | photodynamic therapy basal cell carcinoma |
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