| I型先天性厚甲症一例 |
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| 引用本文： | 刘忠艳,王启华,周桂芝. I型先天性厚甲症一例[J]. 中国麻风皮肤病杂志, 2021, 37(5): 315-316. DOI: 10.12144/zgmfskin202105315 |
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| 作者姓名： | 刘忠艳 王启华 周桂芝 |
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| 作者单位： | 1临沂市皮肤病医院皮肤科，临沂市皮肤病防治所，临沂，276000；2山东第一医科大学附属皮肤病医院（山东省皮肤病医院，山东省皮肤病性病防治研究所），济南，250022 |
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| 摘 要： | 患儿，女，11岁。厚甲、掌跖角化11年，其父亲有类似病史。皮肤科检查：指（趾）甲甲板增厚，口角结黄痂，口唇线状白斑，舌苔厚白，躯干及四肢皮肤多处角化过度。皮肤组织病理示：表皮高度角化过度、角化不全、棘层增厚，真皮乳头血管扩张、充血，周围少许组织细胞浸润。诊断：I型先天性厚甲症。
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Pachyonychia congenita type 1: a case report |
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| LIU Zhongyan,WANG Qihua,ZHOU Guizhi. Pachyonychia congenita type 1: a case report[J]. China Journal of Leprosy and Skin Diseases, 2021, 37(5): 315-316. DOI: 10.12144/zgmfskin202105315 |
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| Authors: | LIU Zhongyan WANG Qihua ZHOU Guizhi |
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| Affiliation: | 1 Department of Dermatology, Linyi Dermatology Hospital, Linyi Institute of Dermatology, Linyi 276000, China; 2 Shandong Provincial Hospital for Skin Diseases & Shandong Provincial Institute of Dermatology and Venereology, Shandong First Medical University, Jinan 250022, China |
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| Abstract: | A 11-year-old female is hereby reported, who presented with subungual hyperkeratosis, yellow scab on the corner of the mouth, oral leukokeratosis and numerous hyperkeratosis lesions all over the body. Histological examination showed hyperkeratosis and parakeratosis of epidermis, acanthosis, dilation and hyperemia of dermal papilla vessels, and histiocytic infiltration surrounding vessels. The features were consistent with a diagnosis of pachyonychia congenita type 1. Her father has a similar history. |
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