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Association between left ventricular perfusion defects and myocardial deformation indexes in heart transplantation recipients |
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| Authors: | Antonello D'Andrea MD PhD Maria Luisa De Rimini MD Raffaella America MD Chiara Cirillo MD Lucia Riegler MD Giuseppe Limongelli MD PhD Michele D'Alto MD PhD Gemma Salerno MD Ciro Maiello MD Pietro Muto MD Maria Giovanna Russo MD Raffaele Calabrò MD Eduardo Bossone MD PhD Giuseppe Pacileo MD |
| Affiliation: | 1. Chair of Cardiology, Monaldi Hospital, AORN Ospedali dei Colli, Luigi Vanvitelli University of Naples, Naples, Italy;2. Department of Nuclear Medicine, Monaldi Hospital, AORN Ospedali dei Colli, Naples, Italy;3. Department of Cardiology and Cardiac Surgery, University Hospital San Giovanni di Dio, Salern, Italy |
| Abstract: | The aim of the study was to analyze possible correlations between strain echocardiography (STE) and PET myocardial perfusion in a population of heart transplantation (HTx) recipients showing preserved left ventricular (LV) ejection fraction. By STE, LV global longitudinal strain (LV GLS) was lower in HTx. PET showed no transient or chronic ischemia in 83 of 115 HTx (73%). Fixed perfusion defects were observed in 17% of HTx and reversible ischemia in 10%. Significant coronary stenosis was observed only in 10 cases. GLS was independently associated with age at HTx and fixed perfusion defects (HR 0.41; P<.001). Such relationships underline STE ability to early identify HTx pts with subclinical myocardial dysfunction during long‐term follow‐up. |
| Keywords: | cardiac PET cardiac transplant cardiopulmonary test doppler echocardiography heart failure two‐dimensional strain |