Differential Recognition of Plasmodium falciparum Merozoite Surface Protein 2 Variants by Antibodies from Malaria Patients in Brazil |
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| Authors: | Kelly A. Kanunfre, Fabiana M. S. Leoratti, Erika H. E. Hoffmann, Rui R. Durlacher, Ant nio W. Ferreira, Sandra L. Moraes- vila, Marcelo U. Ferreira |
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| Affiliation: | Kelly A. Kanunfre, Fabiana M. S. Leoratti, Erika H. E. Hoffmann, Rui R. Durlacher, Antônio W. Ferreira, Sandra L. Moraes-Ávila, and Marcelo U. Ferreira |
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| Abstract: | Four variants of merozoite surface protein 2 (MSP-2) of Plasmodium falciparum were used in serology to examine whether changes in repeat units affect its recognition by antibodies during infection with parasites of known MSP-2 types. The results indicate that variation in MSP-2 repeats may represent a mechanism for parasite immune evasion. |
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