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Overexpression of EZH2 in conjunctival melanoma offers a new therapeutic target
Authors:Jinfeng Cao  Kelly CS Pontes  Renier C Heijkants  Niels J Brouwer  Arwin Groenewoud  Ekaterina S Jordanova  Marina Marinkovic  Sjoerd van Duinen  Amina FAS Teunisse  Robert M Verdijk  Ewa Snaar‐Jagalska  Martine J Jager
Affiliation:1. Department of Ophthalmology, Leiden University Medical Centre, Leiden, The Netherlands;2. Department of Ophthalmology, The Second Hospital of Jilin University, Changchun, PR China;3. Department of Molecular Cell Biology, Institute of Biology, Leiden University, Leiden, The Netherlands;4. Department of Molecular Cell Biology, Leiden University Medical Centre, Leiden, The Netherlands;5. Department of Pathology, Leiden University Medical Centre, Leiden, The Netherlands;6. Centre for Gynaecological Oncology Amsterdam (CGOA), VU University Medical Centre, Amsterdam, The Netherlands;7. Department of Pathology, Section Ophthalmic Pathology, Erasmus MC University Medical Centre, Rotterdam, The Netherlands;8. Department of Ophthalmology, Leiden University Medical Centre, Leiden, The NetherlandsMJJ and AGJ are co‐senior authors.
Abstract:
Keywords:conjunctival melanoma  primary acquired melanosis  EZH2  histone methylation  cell death  zebrafish
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