| 不同面积脾栓塞治疗特发性血小板减少性紫癜及其对脾功能的影响 |
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| 引用本文： | 关红梅,王会丽,魏雪. 不同面积脾栓塞治疗特发性血小板减少性紫癜及其对脾功能的影响[J]. 南方医科大学学报, 2004, 24(3): 343-344 |
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| 作者姓名： | 关红梅 王会丽 魏雪 |
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| 作者单位： | 南阳市第二人民医院血液科, 河南, 南阳, 473000 |
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| 基金项目： | 收稿日期:2003-9-21。作者简介:关红梅(1965- ),女,1986年毕业于河南医科大学,现为南阳市第二人民医院血液科主任,副主任医师,电话:0377-3025276 |
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| 摘 要： | 目的 探讨不同面积的脾栓塞治疗特发性血小板减少性紫癜ITP的效果及其对脾功能的影响。方法 将45例特发性血小板减少性紫癜患者随机分为2组,进行脾栓塞治疗。治疗组(A组)栓塞面积为60%~80%;对照组(B)组栓塞面积为40%~60%。结果 两组患者术后1周内血小板均明显升高;但1年后A组血小板平均值明显高于B组(P<0.01)。治疗前后两组内患者脾功能均无明显变化(P>0.05)。结论 大面积脾栓塞治疗ITP与小面积脾栓塞近期疗效相似,但前者疗效更持久、安全,不影响脾功能,值得推广。
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| 关 键 词： | 紫癜 血小板减少性/外科学 栓塞 治疗性 脾功能亢进/治疗 |
| 文章编号： | 1000-2588(2004)03-0343-02 |
| 修稿时间： | 2003-09-21 |
Partial splenic embolization for idiopathic thrombocytopenic purpura:therapeutic effect and influence of the embolization on splenic function |
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| GUAN Hong-mei,WANG Hui-li,WEI Xue. Partial splenic embolization for idiopathic thrombocytopenic purpura:therapeutic effect and influence of the embolization on splenic function[J]. Journal of Southern Medical University, 2004, 24(3): 343-344 |
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| Authors: | GUAN Hong-mei WANG Hui-li WEI Xue |
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| Affiliation: | GUAN Hong-mei,WANG Hui-li,WEI XueDepartment of Hematology,Second People's Hospital of Nanyang,Nanyang 473000,China |
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| Abstract: | Objective To explore the therapeutic effect of partial splenic embolization of different embolized volumes for idiopathic thrombocytopenic purpura (ITP) and consequent changes of the splenic function. Methods Forty-five ITP patients were randomized into 2 groups to receive splenic embolization with gelatin sponge particles, and the embolized volume ranged between 60% and 80% in the former group (group A), and between 40% and 60% in the latter group (group B). Results The platelet counts of the patients in both groups markedly increased one week after the operation, and the average count was significant higher in group A than in group B one year after the operation (P<0.01). The splenic function of the patients in neither of groups underwent any significant changes after the operation (P>0.05). Conclusion Splenic embolization of different volumes produces similar therapeutic effect on ITP, but more extensive embolization may insure long-lasting effect with better safety and less influence on splenic function. |
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| Keywords: | purpura thrombocytopenic/surgery therapeutic embolization hypersplenism/therapy |
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