In Vitro Activity of Rosamicin and Erythromycin Against a Group of Nonfermenting Gram-Negative Bacilli |
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| Authors: | Joseph R. DiPersio and Theodore L. Krafczyk |
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| Affiliation: | 1Department of Laboratory Medicine, The Christ Hospital, Cincinnati, Ohio 45219 |
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| Abstract: | The in vitro inhibitory activity of rosamicin and erythromycin against 283 strains of nonfermenting, gram-negative bacilli was determined by using a broth dilution procedure. Rosamicin demonstrated greater activity than erythromycin against most strains tested. A number of species demonstrated significantly lower minimum inhibitory concentrations to rosamicin and would fall within the therapeutic range of the drug based on current pharmacological data. |
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