| 一起腺病毒引起的咽结膜热爆发 |
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| 引用本文： | 刘小平,ZHANG Yu-min,张玉敏,薄福宝,李志忠,王大伟,宋永胜,王红霞,周滨鹏,云中平,任先云,许汝琪,许向云,郭淑怡. 一起腺病毒引起的咽结膜热爆发[J]. 疾病监测, 2007, 22(6): 381-383. DOI: 10.3784/j.issn.1003-9961.2007.6.381 |
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| 作者姓名： | 刘小平 ZHANG Yu-min 张玉敏 薄福宝 李志忠 王大伟 宋永胜 王红霞 周滨鹏 云中平 任先云 许汝琪 许向云 郭淑怡 |
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| 作者单位： | 呼和浩特市疾病预防控制中心,内蒙古,呼和浩特,010020;呼和浩特市疾病预防控制中心,内蒙古,呼和浩特,010020;呼和浩特市疾病预防控制中心,内蒙古,呼和浩特,010020;呼和浩特市疾病预防控制中心,内蒙古,呼和浩特,010020;呼和浩特市疾病预防控制中心,内蒙古,呼和浩特,010020;呼和浩特市疾病预防控制中心,内蒙古,呼和浩特,010020;呼和浩特市疾病预防控制中心,内蒙古,呼和浩特,010020;呼和浩特市疾病预防控制中心,内蒙古,呼和浩特,010020;呼和浩特市疾病预防控制中心,内蒙古,呼和浩特,010020;呼和浩特市疾病预防控制中心,内蒙古,呼和浩特,010020;呼和浩特市疾病预防控制中心,内蒙古,呼和浩特,010020;呼和浩特市疾病预防控制中心,内蒙古,呼和浩特,010020;呼和浩特市疾病预防控制中心,内蒙古,呼和浩特,010020;呼和浩特市疾病预防控制中心,内蒙古,呼和浩特,010020 |
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| 基金项目： | 对此次疫情处理给予大力技术支持的中国疾病预防控制中心病毒病预防控制所许文波研究员和内蒙古自治区疾病预防控制中心吴秉仁主任等一并致谢! |
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| 摘 要： | 目的 查明2005年7～8月发生在呼和浩特市一起儿童少年游泳后出现发热、咽痛、扁桃体红肿、眼结膜充血为特征的咽结膜热爆发的病原学病因和流行因素.方法 制定病例临床诊断标准,采用统一的流行病学个案调查表对病例进行调查,描述流行特征;采用回顾队列调查的方法分析流行因素;对患者咽拭子、便标本进行聚合酶链反应(PCR)、对患者的血清进行抗体检测.结果 2005年7～8月,呼和浩特市发生咽结膜热病例468例,疫情波及呼市四个市区,发病高峰为8月2日,病例主要为中小学生.病例的临床特征为发热伴咽痛、扁桃体炎、结膜炎.预后良好,无死亡病例.病例95.05%有游泳史.回顾队列调查显示发病危险因素与游泳馆游泳池水污染有关.PCR检测及血清学检测证实为腺病毒感染.对PCR阳性产物进行序列测定和分析,确定为腺病毒3型.结论 发生在呼和浩特市咽结膜热爆发疫情的病原体为腺病毒,爆发主要是通过被污染游泳池水传播造成的.
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| 关 键 词： | 腺病毒 咽结膜热 爆发 游泳池水 |
| 文章编号： | 1003-9960（2007）06-0381-03 |
| 收稿时间： | 2007-02-05 |
| 修稿时间： | 2007-02-05 |
An outbreak of pharyngoconjunctival fever caused by adenovirus |
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| ZHANG Yu-min. An outbreak of pharyngoconjunctival fever caused by adenovirus[J]. Disease Surveillance, 2007, 22(6): 381-383. DOI: 10.3784/j.issn.1003-9961.2007.6.381 |
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| Authors: | ZHANG Yu-min |
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| Affiliation: | 1.Hohhot Municipal CDC of Inner Mongolia;Hohhot;Inner Mongolia 010070 China |
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| Abstract: | Objective The present study was conducted to investigate the pathogenic and epidemic factors of an outbreak of pharyngoconjunctival fever characterized by fever,angina,tonsillitis and con- junctival congestion after swimming among juvenile in Hohhot from July to August,2005.Methods The established clinical diagnostic standard and uniform epidemiological questionnaires were used to investigate the cases and to describe the epidemic characteristics.The epidemic factors were analyzed by Cohort study,PCR was performed on patients' pharyngeal swabs and stool samples,and serum antibodies were detected.Results There were 468 cases of pharyngoconjunctival fever,involving mostly middle and primary school students.The epidemic covered four urban districts with a peak oc- curred on August 2nd.The clinical characteristics were fever accompanied by angina,tonsillitis and conjunctivitis.The prognosis was good and no death was reported;95.05% of the patients had the his- tory of swimming.The Cohort study showed that the risk factors were associated with the pollution of swimming pools.Adenovirus infection was revealed by PCR and serological assay,and it was further confirmed to be adenovirus type 3 after performing gene sequencing on the PCR positive samples. Conclusion The pathogenic agent of pharyngoconjunctival fever breaking out in Hohhot was con- fumed to be adenovirus,and the polluted water in swimming pools was the main route of transmission. |
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| Keywords: | adenovirus pharyngoconjunctival fever outbreak swimming pool water |
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