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胰岛素抵抗与急性脑梗死严重程度关系研究
引用本文:罗雪丹.胰岛素抵抗与急性脑梗死严重程度关系研究[J].中国实用神经疾病杂志,2009,12(6).
作者姓名:罗雪丹
作者单位:沈阳市第一人民医院,沈阳,110041
摘    要:目的 探讨胰岛素抵抗与急性脑梗死严重程度的关系.方法 选取急性脑梗死患者75 例,按神经功能缺损评分标准将急性脑梗死组分为神经功能缺损轻型组和中重型组,对照组为同期门诊健康体检者55例.各组分别检测空腹血糖、空腹血清胰岛素、纤维蛋白原、总胆固醇、甘油三酯、低密度脂蛋白胆固醇、高密度脂蛋白胆固醇、载脂蛋白A蛋白、载脂蛋白B蛋白、尿酸,计算体重指数、胰岛素敏感指数、胰岛素抵抗指数,进行统计学分析.结果 急性脑梗死组FPG、FINS、HOMA-IR、FIB显著高于对照组,急性脑梗死神经功能缺损中重型组中FPG、FINS、HOMA-IR显著高于轻型组,差异均有统计学意义.结论 急性脑梗死患者存在IR,神经功能缺损中重型组较轻型组存在更严重的IR,并且IR 程度与神经功能缺损的严重程度有关.

关 键 词:急性脑梗死  胰岛素抵抗  神经功能缺损

Study on relationship between insulin resistance and the severity of acute cerebral infarction
Luo Xuedan.Study on relationship between insulin resistance and the severity of acute cerebral infarction[J].Chinese Journal of Practical Neruous Diseases,2009,12(6).
Authors:Luo Xuedan
Institution:Luo Xuedan.Shenyang First People's Hospital,Shenyang 110041,China
Abstract:Objective To investigate the relationship between IR and the severity of acute cerebral infarction.Methods Patients diagnosed with acute cerebral infarction were chosen.The FPG,FINS,FIB,TC,TG,LDL,HDL,ApoA,ApoB,UA,NSE were detected in two groups at the same time.The body mass index(BMI),insulin sensitivity index(ISI),insulin resistance index(HOMA-IR)were calclated.Then the statistics were entered into the computer and analyzed by SPSS statistic analysis software.Results There were significant differences in ...
Keywords:Acute cerebral infarction  Infarction resistance  Neurol function defect  
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