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立体定向放射治疗脑动静脉畸形38例分析
引用本文:董玲,王静,张玫.立体定向放射治疗脑动静脉畸形38例分析[J].中国实用神经疾病杂志,2008,11(5):50-52.
作者姓名:董玲  王静  张玫
作者单位:1. 河南科技大学第一附属医院放疗科,洛阳,471003
2. 洛阳理工学院校医院,洛阳,471003
摘    要:目的分析立体定向放射治疗脑动静脉畸形(AVM)的方法、疗效。方法设置靶点数1~2个,靶点边缘剂量18~25Gy(平均20.4Gy),70%~85%等剂量线覆盖病灶,采用600C直线加速器6mv X线对38例脑动静脉畸形患者实施非共面、旋转照射。结果随访1~36个月,平均26个月,2年内AVM完全闭塞78.9%,部分闭塞15.7%,无变化5.4%,癫缓解率83%,头痛缓解率78%。2例于2周内出现急性脑水肿症状,6~8个月影像显示18例慢性脑水肿,其中2例出现临床症状,均经对症处理症状缓解。结论立体定向放射治疗对深部或重要功能区的AVM、术后残留或不能、不愿手术者是一种安全有效的方法。

关 键 词:动静脉畸形  立体定向  放射治疗
文章编号:1673-5110(2008)05-0050-03
修稿时间:2008年3月10日

Analysis of 38 cases of brain arteriovenous malformations by stereotactic locating radiotherapy
Dong Ling,Wang Jing,Zhang Mei.Analysis of 38 cases of brain arteriovenous malformations by stereotactic locating radiotherapy[J].Chinese Journal of Practical Neruous Diseases,2008,11(5):50-52.
Authors:Dong Ling  Wang Jing  Zhang Mei
Abstract:Objective To analyze and evaluate the method and curative effect of stereotactic radiotherapy(SRT) for brain arteriovenous malformations(AVM).MethodsTarget numbers were setted.The peripheral does were 18~25Gy(average 20.4Gy).The focus was covered by 70%~85% equal dose line.Thirty-eight patients with AVM were treated by noncoplanarity and rotating radiotherapy through 6mV X-ray 600C linear accelerator.ResultsThe follow-up period ranged from 1 to 36 months(average 26 months).Within 2 years,78.9% patients were obturated completely,15.7% obturated partly,5.4% unchanged.Falling sickness relieved 83% after radiosurgery,headache relieved 78%.2 patients appeared acute hydrocephalus within two weeks.18 patients appeared chronic hydrocephalus within 6~8 months by image display.2 patients had clinical symptom.The symptom was relieved after treatment.ConclusionStereotactic locating radiotherapy will be a safe treatment method for AVM with deep and important function place,as well as patients have rudimental symptom after operation or can't and don't want to be operated.
Keywords:Arteriovenous malformations  Stereogram locating technique  Radiationtherapy
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