醒脑静注射液治疗急性缺血性脑卒中的临床疗效及对炎性因子的影响

目的探讨醒脑静注射液治疗急性缺血性脑卒中的疗效及对炎性因子的影响。方法选择急性缺血性脑卒中患者80例,随机分为观察组与对照组各40例,对照组给予常规治疗,观察组在对照组治疗基础上加用醒脑静注射液治疗,对比2组患者治疗前后的有效率、神经功能缺损情况、日常生活能力改善情况、对炎性因子的影响。结果 2组患者神经功能评分与日常生活能力评分治疗后均显著优于治疗前(P0.05),且治疗后观察组显著优于对照组(P0.05);观察组总有效率95.0%,显著高于对照组的72.5%(P0.05),治疗后2组患者CRP、IL-6、TNF-α比较差异具有统计学意义(P0.05)。结论急性缺血性脑卒中患者常规治疗基础上加用醒脑静注射液治疗,疗效显著,对改善患者神经功能具有积极作用,可显著抑制炎症反应。

Clinical effect of Xingnaojing injection on acute ischemic stroke and on inflammatory factors

Objective To discuss the clinical effect of Xingnaojing injection on acute ischemic stroke and on infla mmatory factors.Methods 80 patients withacute ischemic stroke were divided into the observation group(n =40)and the control group (n=40),patients in control group were given traditional treatment,observation group received Xingnaojing injection based on the control group,then the clinical effectand infla mmatory factors were contrasted between the two groups.Results The nerve functionandability of daily life were significantly better in both groupsafter the treatment(P <0.05),and the observation group was superior to the control group (P <0.05);The observation group got the total effective rate of 95.0%,significantlyhigher than 72.5% in control group (P <0.05);inaddition,after the treatment,the detection of CRP,IL-6and TNF-αshowed statis-tical difference between two groups (P <0.05).Conclusion The theraPY of Xingnaojing injection combined with the conven-tional treatmenthas curative effect onacute ischemic stroke,which can not only effectively improve the neurological functionand the livingability of the patients,butalso inhibit the reaction of infla mmation.