2型糖尿病患者轻度认知功能障碍的临床分析

目的探讨2型糖尿病患者轻度认知功能障碍的特点。方法将122例2型糖尿病患者分为伴2型糖尿病轻度认知功能障碍组(45例)、不伴2型糖尿病轻度认知功能障碍组(41例)和对照组(36例),使用蒙特利尔认知评估量表(montreal cognitive assessme,MoCA)对患者的命名、注意、视空间/执行功能、持续注意、语言、计算、抽象、定向力、延迟回忆进行评分评估。结果与对照组比较,伴2型糖尿病轻度认知功能障碍组在命名、注意、视空间/执行功能、持续注意、语言、计算、抽象、定向力、延迟回忆等评分比较差异具有统计学意义(P0.01)。与不伴2型糖尿病MCI组比较,伴2型糖尿病MCI组在总分、视空间/执行功能、注意、持续注意、延迟回忆等评分2组间差异有统计学意义(P0.05)。结论伴2型糖尿病的MCI患者在命名、注意、视空间/执行功能、持续注意、语言、计算、抽象、定向力、延迟回忆等方面有不同程度的损害;其总体认知功能损害较不伴2型糖尿病者严重,尤其在视空间/执行能力、注意、持续注意及记忆方面。

Clinical analysis of mild cognitive impairment patients with type 2 diabetes mellitus

Objective To explore the characteristics of the mild cognitive impairment (MCI) of patients with type 2 diabetes mellitus (T2DM).Methods All research subjects are divided into MCI with T2DM group (45 patients),MCI without T2DM group (41 patients) and control group (36 participants).The Montreal cognitive assessment (MoCA) was administered to all subjects to test their view space /executive capability,name,attention,sustain attention,calculate,language,abstract,and delay recall.Results Compared with control group,the MCI with T2DM group had significantly lower scores in visual spatial/executive capability,attention,sustain attention,language,abstract,delay recall (P<0.01).Compared with the MCI without T2DM group,the total scores of MCI with T2DM group were significantly lower,and they had significantly lower scores in visual spatial/executive capability,attention,sustain attention,delay recall (P<0.01-0.05).Conclusion The visual spatial/executive capability,attention,sustain attention,language,abstraction and memory of the MCI patients with T2DM are impaired unequally.The total cognitive function of MCI patients with T2DM is poorer than the MCI patients without T2DM,especially in visual spatial/executive capability,attention,sustain attention and memory.