| 名人面孔、动物和人造物类别特异性命名区脑定位的功能磁共振研究(英文) |
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| 引用本文： | 白红民,江涛,王伟民,李天栋,刘严,卢亦成.名人面孔、动物和人造物类别特异性命名区脑定位的功能磁共振研究(英文)[J].中国神经科学杂志,2011(5). |
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| 作者姓名： | 白红民 江涛 王伟民 李天栋 刘严 卢亦成 |
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| 作者单位： | 第二军医大学长征医院神经外科;广州军区广州总医院神经外科;首都医科大学附属北京天坛医院胶质瘤中心; |
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| 基金项目： | supported bythe Foundation of Science and Technology Program of Guangdong Province,China(No.2008A030201021); the Natural Science Foundation of Guangdong Province,China(No.10151001002000010) |
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| 摘 要： | 目的在一些疾病中,病人会出现类别特异性的识别和命名障碍,但有关名人面孔、动物和人造物三种不同类型命名任务的脑定位研究仍存在争议。本研究旨在利用功能磁共振(fMRI)研究这三种不同类型命名任务的脑激活特点。方法采用SPM8软件进行脑功能图像分析,命名任务与基线任务采用t检验统计,然后进行群组分析,结果用MNI坐标表示,解剖位置用XJview8自动标记。结果名人面孔命名区主要位于双侧前颞叶包括海马和杏仁核,且存在左侧优势,同时还激活双侧颞下回三角部和盖部;命名动物主要激活左侧辅助运动区;而命名人造物主要激活左侧运动前区和右侧辅助运动区,三种任务均有双侧梭状回激活,但命名人造物激活区范围比其余两种任务都大。结论人、动物和人造物三种不同类型命名任务的脑定位存在差异,这提示在术中定位功能区过程中,需要选择不同类型的命名任务,以减少阴性刺激和术后永久性功能障碍的发生率。
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| 关 键 词： | 脑定位 类别特异性命名 名人面孔 动物 人造物 |
Functional MRI mapping of category-specific sites associated with naming of famous faces,animals and man-made objects |
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| Hong-Min Bai ,Tao Jiang ,Wei-Min Wang ,Tian-Dong Li ,Yan Liu ,Yi-Cheng Lu Neurosurgical.Functional MRI mapping of category-specific sites associated with naming of famous faces,animals and man-made objects[J].Neuroscience Bulletin,2011(5). |
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| Authors: | Hong-Min Bai Tao Jiang Wei-Min Wang Tian-Dong Li Yan Liu Yi-Cheng Lu Neurosurgical |
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| Institution: | Hong-Min Bai 1,2,Tao Jiang 3,Wei-Min Wang 2,Tian-Dong Li 2,Yan Liu 2,Yi-Cheng Lu 1 1 Neurosurgical Department of Changzheng Hospital,the Second Military Medical University,Shanghai 200003,China 2 Neurosurgical Department of Liuhuaqiao Hospital,Guangzhou 510010,China 3 Department of Neurosurgery,Tiantan Hospital,Beijing 100050,China |
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| Abstract: | Objective Category-specific recognition and naming deficits have been observed in a variety of patient populations. However, the category-specific cortices for naming famous faces, animals and man-made objects remain controversial. The present study aimed to study the specific areas involved in naming pictures of these 3 categories using functional magnetic resonance imaging. Methods Functional images were analyzed using statistical parametric mapping and the 3 different contrasts were evaluated using t sta... |
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| Keywords: | brain mapping category-specific naming famous face animal man-made object |
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