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Pallidal deep brain stimulation in the treatment of Meige syndrome |
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| Authors: | P Blomstedt S Tisch M I Hariz |
| Institution: | Department of Neurosurgery, University Hospital of Northern Sweden, Umeå, Sweden;;Institute of Neurology, Queen Square, London, UK |
| Abstract: | Background – Pallidal deep brain stimulation (DBS) of globus pallidus internus (Gpi) has emerged as an effective treatment for dystonia. The experience is however limited concerning focal dystonias and to date only a few cases of pallidal DBS in the treatment of Meige syndrome have been published. Methods/results – We here present a patient with Meige syndrome in whom unilateral pallidal DBS failed to improve the axial symptoms, but bilateral stimulation resulted in a major improvement. The Burke-Fahn-Marsden score (BFM) improved by 71.5% and the patient's blepharospasm was abolished. Conclusions – The results suggest bilateral pallidal DBS may be an effective treatment for Meige syndrome. |
| Keywords: | DBS dystonia Meige syndrome pallidal stimulation |