Central Nervous System Lymphomatoid Granulomatosis Presenting with Parkinsonism |
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| Authors: | Eun Hee Sohn Chang Joon Song Hyo-Jin Lee Samyong Kim Jae-Moon Kim and Ae Young Lee |
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| Institution: | aDepartment of Neurology, Chungnam National University, Daejeon, Korea.;bDepartment of Radiology-Neuroradiology, Chungnam National University, Daejeon, Korea.;cDepartment of Internal Medicine-Oncology, Chungnam National University, Daejeon, Korea. |
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| Abstract: | Lymphomatoid granulomatosis (LG) is a potentially malignant lymphoproliferative disorder. The lung is the most common involved site, followed by the skin and nervous system. However, LG of the central nervous system presenting with Parkinsonism is very rare. We report a patient with LG who presented with parkinsonian features such as bilateral rigidity, bradykinesia, and agitation. Brain magnetic resonance imaging showed multifocal punctuate enhanced lesions in both supra- and infratentorial areas. Steroid pulse therapy resulted in a dramatical improvement in the symptoms and MRI abnormalities. |
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| Keywords: | Lymphomatoid granulomatosis Parkinsonism Magnetic resonance imaging |
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