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Complete Remission of Neuroleptic-Induced Meige's Syndrome by Botulinum Toxin Treatment: A Case Report
Authors:Kouichi Kurata MD  PhD    Shouge Kuze MD  Ryoko Shibata MD    Noboru Hatakeyama MD  Akira Masuda MD  Yusuke Ito MD  Masayoshi Kurachi MD
Institution:Department of Neuropsychiatry, Faculty of Medicine, Toyama Medical and Pharmaceutical University, Toyama;*Department of Anesthesiology, Faculty of Medicine, Toyama Medical and Pharmaceutical University, Toyama
Abstract:Abstract: A botulinum A toxin injection has beneficial effects on patients suffering from facial and cervical spastic disorders. However, its effect almost completely disappears within three months. We have reported a case of a 23-year-old schizophrenic patient with severe neuroleptic-induced Meige's syndrome in whom botulinum toxin treatment exerted a marked effect which lasted more than 15 months after the final injection of botulinum toxin in spite of continuous neuroleptic medication. It is concluded that botulinum can be recommended as a treatment of choice in neuroleptic-induced Meige's syndrome.
Keywords:neuroleptics  tardive dystonia  Meige's syndrome  botulinum toxin
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