| 30名健康儿童的感觉门控P50研究 |
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| 引用本文： | 吕坚,黄军斌,吴荣琴,李桦,孙复林,徐璐,钱玲萍,陈兴时.30名健康儿童的感觉门控P50研究[J].神经病学与神经康复学杂志,2012,9(1):4-6. |
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| 作者姓名： | 吕坚 黄军斌 吴荣琴 李桦 孙复林 徐璐 钱玲萍 陈兴时 |
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| 作者单位： | 1. 上海市闸北区精神卫生中心精神科,上海,200436
2. 上海交通大学医学院附属精神卫生中心神经生理室,上海,200030 |
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| 基金项目： | 上海市闸北区卫生局课题 |
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| 摘 要： | 目的 应用诱发电位新技术探讨健康儿童感觉门控 (SG) P50特点.方法 应用美国Nicolet脑电生理仪,采用条件刺激(S1)-测试刺激(S2)模式对30名健康儿童进行听觉P50检测.结果 健康儿童Cz脑区S1-P50潜伏期(60.7±11.9)ms,波幅(5.7±3.3)μV;S2-P50潜伏期(65.4±22.0)ms,波幅(2.4±1.3)μV.S2-P50波幅显著低于S1-P50(P<0.01).S2/S1比值为(42.8±21.0)%;S1-S2波幅和100(1-S2/S1)波幅分别为(3.3±2.6)μV和(57.9±21.0)μV.结论 听觉P50电位具有抑制性特征,其变化可反映大脑健康儿童SG的功能状态.
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| 关 键 词： | 健康儿童 诱发电位 P50 感觉门控 |
Study of sensory gating P50 on 30 normal children |
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| Lv Jian
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Huang Junbin
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Wu Rongqian
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Li Hua
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Sun Fulin
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Xu Lu
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Qian Linping
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Chen Xingshi.Study of sensory gating P50 on 30 normal children[J].Journal of Neurology and Neurorehabilitation,2012,9(1):4-6. |
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| Authors: | Lv Jian Huang Junbin Wu Rongqian Li Hua Sun Fulin Xu Lu Qian Linping Chen Xingshi |
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| Institution: | 1Department of Psychiatric,Shanghai Zhabei Mental Health Center,Shanghai 200436,China;2Department of Electrophysiology,Shanghai Mental Health Center,Shanghai Jiaotong University,Shanghai 200030,China) |
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| Abstract: | Objective To observe the characteristics of sensory gating P50 in normal children.MethodsUsing American Nicolet Bravo instrument,auditory evoked potentials P50 were recorded in 30 normal children by the conditioning(S1)/testing(S2) paradigm presented with auditory double clicks stimuli.Results The latencies of S1-P50 and S2-P50 from Cz site were(65.4±22.0) ms and(65.4±22.0)ms while the amplitudes were(5.7±3.3)μV and(2.4±1.3)μV,respectively.S2-P50 amplitude reduced significantly as compared with S1-P50 amplitude(P<0.01).The S2/S1 ratio was(42.8±21.0%) and the amplitudes of S2-S1 and 100(1-S2/S1) were(3.3±2.6)μV and(57.9±21.0)μV.Conclusion The auditory evoked potential P50 has the potential inhibitory characteristics,the changes may reflect the functional status of SG in normal children. |
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| Keywords: | normal children evoked potentials P50 sensory gating |
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