Relationship of Ferritin to Symptom Ratings Children with Attention Deficit Hyperactivity Disorder: Effect
of Comorbidity |
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Authors: | Pinar Oner Ozgur Oner |
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Institution: | (1) Child Psychiatry Department, Ataturk Hospital, Ankara, Turkey;(2) Gelincik Sok 11/10 A. Ayranci, Ankara, Turkey;(3) Child Psychiatry Department, Diskapi Children’s Hospital, Ankara, Turkey;(4) Fogarty International Center Mental Health and Developmental Disabilities Program, Children’s Hospital, Boston, USA |
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Abstract: | Our aim was to investigate the relation between behavioral symptoms and hematological variables which are related with iron
deficiency and anemia, ferritin, hemoglobin, mean corpuscular volume (MCV), and reticulosite distribution width (RDW) in children
and adolescents with pure Attention Deficit Hyperactivity Disorder (ADHD) or ADHD comorbid with other psychiatric disorders.
The sample consisted of 151 subjects with ADHD, 45 of these subjects had other comorbid conditions. Conners Parent (CPRS)
and Teacher Rating Scales (CTRS) were obtained. Comorbid ADHD subjects had lower mean hemoglogin and MCV. In the ADHD group
in general, CPRS and CTRS Total scores were significantly negatively correlated with ferritin level. When only pure ADHD subjects
were taken into account, the correlations did not reach statistical signifance. Overall, these results suggested that lower
ferritin level was associated with higher behavioral problems reported by both parents and teachers. Presence of comorbid
conditions might increase the effect of lower iron stores on behavioral measures. |
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Keywords: | Attention Deficit Hyperactivity Disorder Ferritin Comorbidity |
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