H型高血压与急性脑梗死患者颈动脉粥样硬化斑块的相关性分析

目的探讨H型高血压与急性脑梗死患者颈动脉粥样硬化斑块形成的相关性。方法将132例患者分为斑块组和无斑块组（对照组）,采用循环酶法测定血浆Hcy水平,比较H型高血压亚组、高血压亚组、高Hcy血症亚组（无高血压）及正常亚组颈动脉粥样斑块的检出率。结果颈动脉超声诊断显示,132例患者中99例患者存在颈动脉粥样硬化斑块,其余33例患者未发现。2组性别、年龄、吸烟、饮酒史、糖尿病史等比较差异无统计学意义（P〉0.05）。斑块组中不同亚组检出率依次为H型高血压亚组〉高Hcy血症亚组〉高血压亚组〉正常组,差异有统计学意义（P〈0.05）。结论 H型高血压与颈动脉粥样硬化斑块的形成密切相关,为急性脑梗死患者颈动脉粥样硬化斑块形成的独立危险因素。

Relationship between H--type hypertension and carotid atherosclerotic plaque in patients with acute cerebral infarction

Objective To investigate the relationship between H-type hypertension and carotid atherosclerotic plaque in patients with acute cerebral infarction. Methods One hundred and thirty-two cases of patients were divided into plaque group and no plaque group （the control group） ,and the plasma Hcy levels were determined by cyclic enzymatic method.The carotid plaque detection rate of H-hypertensive subgroup ,hypertensive subgroup ,high Hcy subgroup （without hypertension） and normal subgroup were compared. Results The carotid ultrasound showed that 99 patients had carotid atherosclerotic plaques ,and the remaining 33 patients were with no carotid atherosclerotic plaques.There was none statistically significant difference of the gender ,age ,smoking ,drinking and diabetes history between the two groups （P〉0.05）.The H-type history rate of the plaque group was higher than that of the control group （P〈0.05）. The plaque detection rates in different subgroups were as follows ：H-type hypertensive subgroup〉high Hcy blood subgroups〉hypertensive subgroup〉normal group. And the detection rate of the H-hypertensive subgroup of the plaque group was higher than that of the control group （P〈0.05）. Conclusion There is a close relation between the H-type hypertension and carotid atherosclerosis plaque formation ,H-type hypertension is an independent risk factor for carotid atherosclerotic plaque formation in patients with acute cerebral infarction.