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磁共振波谱分析对轻微型肝性脑病患者的诊断价值
引用本文:张勇,张金彪,李振芝,王鹏飞,孙海荣.磁共振波谱分析对轻微型肝性脑病患者的诊断价值[J].临床神经病学杂志,2009,22(2).
作者姓名:张勇  张金彪  李振芝  王鹏飞  孙海荣
作者单位:1. 山东威海市立医院神经内科,264200
2. 山东威海市立医院磁共振室,264200
摘    要:目的研究磁共振波谱分析(MRS)对轻微型肝性脑病(MHE)患者的诊断价值。方法应用3.0MR机对26例MHE患者进行扣带回和额叶的单体素点分辨自旋回波波谱序列扫描。计算N-乙酰天门冬氨酸(NAA)、肌酐(Cr)、胆碱(Cho)、肌醇(mI)和谷氨酰胺复合物(Glx)的峰下面积,计算NAA/Cr、Cho/Cr、mI/Cr、Glx/Cr的值,并与正常对照组比较。结果与正常对照组相比,MHE组扣带回和额叶的Cho/Cr、mI/Cr显著降低(P<0.01~0.001),Glx/Cr值显著升高(均P<0.005),NAA/Cr值差异无统计学意义(均P>0.05)。结论MHE患者MRS检查显示扣带回和额叶Cho、mI水平降低,Glx水平升高,MRS对MHE的诊断有显著价值。

关 键 词:肝性脑病  磁共振波谱分析  扣带回  额叶  

Diagnostic value of proton magnetic resonance spectroscopy in patients with minimal hepatic encephalopathy
ZHANG Yong,ZHANG Jin-biao,LI Zhen-zhi,et al..Diagnostic value of proton magnetic resonance spectroscopy in patients with minimal hepatic encephalopathy[J].Journal of Clinical Neurology,2009,22(2).
Authors:ZHANG Yong  ZHANG Jin-biao  LI Zhen-zhi  
Institution:ZHANG Yong,ZHANG Jin-biao,LI Zhen-zhi,et al.Department of Neurology,Sh,ong Weihai Municipal Hospital,Weihai 264200,China
Abstract:Objective To study the diagnostic value of proton magnetic resonance spectroscopy(MRS) in patients with minimal hepatic encephalopathy(MHE).Methods MRS of cingulated cortex and frontal lobe were acquired using point resolved echo spin spectroscopy(PRESS) sequences in 26 patients with MHE.Peak area of each metabolite,including NAA,Cr,Cho,mI,Glx and their ratios to Cr were computed,respectively.Then the results were compared with normal control group.Results Compared with the normal control group,MHE group sh...
Keywords:hepatic encephalopathy  magnetic resonance spectroscopy  cingulate cortex  frontal lobe  
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