急性重症脑梗死患者脑血流灌注状态及其与预后的关系

目的 探讨急性重症脑梗死患者脑血流灌注状态及其与预后的关系.方法 回顾性分析10例急性重症脑梗死患者的临床及MR资料.结果 本组患者患侧局部脑血流量(rCBF)和局部脑血容量(rCBV)明显下降9例(90%),与对侧脑组织相比分别降低64.1%和49.7%,两侧比较有统计学意义(P=0.001;P=0.01);MRA显示本组10例患者(100%)患侧大血管(颈内动脉或大脑中动脉)均闭塞,同时合并对侧大血管狭窄或闭塞7例(70%).死亡2例,重残8例.结论 急性重症脑梗死患者的脑血流灌注明显降低,预后很差.

Relationship between the cerebral blood flow filling condition and prognosis of patients with acute severe cerebral infarction

Objective To investigate the relationship between the cerebral blood flow filling condition and prognosis of patients with acute severe cerebral infarction.Methods The clinical data and MR features of 10 cases of acute severe cerebral infarction were retrospectively analyzed.Results The regional cerebral blood flow(rCBF) and regional cerebral blood volume(rCBV) of 9 cases(90%) in the infarcted side decreased significantly.The reduced percents of the infarcted side reached 64.1% and 49.7% respectively.There were significant differences between two opposite sides(P=0.001,P=0.01).The MRA results showed great vessels(arteria carotis interna or arteria cerebri media) in the infarcted side were all obliterated in the all patients,and simultaneous great vessels in opposite side were narrow or occlusion in 7 cases(70%).2 cases died;and 8 cases were serious disability.Conclusions The cerebral blood flow filling of the acute severe cerebral infarction patients decrease significantly.The prognosis of the patients is quite bad.