脑梗死患者颈动脉粥样硬化斑块形成的研究

目的 探讨脑梗死(CI)患者颈动脉粥样硬化斑块形成的状况.方法 对138例CI患者行颈动脉彩色多普勒超声检查,观察其颈动脉斑块形成、性质及部位,并与正常对照组比较.结果 CI组138例中120例(87.7%)检出颈动脉粥样硬化斑块175块,正常对照组140人检出斑块为36人(25.7%)(P＜0.01).CI组中不稳定性斑块比率(80.8%)显著高于稳定性斑块(19.2%)(P＜0.01);斑块位于颈总动脉(CCA)(81.1%)显著高于颈内动脉(ICA)(18.9%)(P＜0.01);位于CCA分叉处(66.3%)又显著高于主干(14.9%)(P＜0.05).结论 CI患者颈动脉粥样硬化斑块的发生率高,多位于CCA分叉处,且大多为不稳定性斑块.提示CI与颈动脉粥样硬化有密切关系.

Study on the incidence of the carotid artery atherosclerotic plaque in patients with cerebral infarction

Objective To explore the incidence of the carotid artery atherosclerotic plaque in patients with cerebral infarction(CI).Methods 138 CI patients on their carotid artery were examed with color doppler ultrasonography.The incidence,stability and location of the carotid artery atherosclerotic plaque in CI patients were observed and compared with those of the normal controls.Results 120 cases(87.7%) of the 138 CI patients were turned out 175 atherosclerotic plaques.36 cases of the 140 normal controls were turned out to be with atherosclerotic plaque(25.7%).There was significant difference between the two groups(P<0.01).In the CI group,the rate of unstable plaque(80.8%) was higher than that of stable plaque(19.2%)(P<0.01).The rate of the atheromatous plaques in common carotid artery(CCA)(81.1%) was higher than that in internal carotid artery(ICA)(18.9%)(P<0.01).The rate of the atheromatous plaques in bifurcation of CCA(66.3%) was higher than that in the trunk of CCA(14.9%)(P<0.05).Conclusion The incidence of the carotid artery atherosclerosis plaque in patients with CI is higher.Most of plaques are situated in the bifurcation of the CCA,and are unstable plaques,which indicale that there is a significant relationship between the carotid artery atherosclerosis and the CI.