| 副肿瘤性边缘叶脑炎的临床和影像学特征 |
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| 引用本文： | 徐全刚,吴卫平,尹岭. 副肿瘤性边缘叶脑炎的临床和影像学特征[J]. 临床神经病学杂志, 2003, 16(3): 134-136 |
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| 作者姓名： | 徐全刚 吴卫平 尹岭 |
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| 作者单位： | 100853,中国人民解放军总医院神经内科 |
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| 摘 要： | 目的 探讨副肿瘤性边缘叶脑炎(PLE)的临床和影像学特征。方法 报告2例PLE患者(分别合并侵袭性胸腺瘤及肺癌)的临床、实验室及影像学资料。结果 2例均有癫痫发作、记忆及定向降碍、明显精神异常。头颅MRI均表现为颞叶海马长T1、长T2信号。1例在急性期胸部正电子发射扫描(PET)表现为病灶部位放射性浓集。结论 临床表现及影像学检查是诊断PLE的重要手段。
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| 关 键 词： | 副肿瘤性边缘叶脑炎 影像学检查 诊断 临床资料 临床表现 头颅MRI |
| 文章编号： | 1004-1648(2003)03-0134-03 |
| 修稿时间： | 2002-09-25 |
The clinical and imaging features of paraneoplastic limbic encephalitis |
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| Xu Quangang,Wu Weiping,Yin Ling. The clinical and imaging features of paraneoplastic limbic encephalitis[J]. Journal of Clinical Neurology, 2003, 16(3): 134-136 |
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| Authors: | Xu Quangang Wu Weiping Yin Ling |
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| Affiliation: | Xu Quangang,Wu Weiping,Yin Ling. Department of Neurology,General Hospital of PLA,Beijing 100853,China |
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| Abstract: | Objective To study the clinical and imaging features of paraneoplastic limbic encephalitis (PLE). Methods The clinical, latoratorial and imaging information of two patients with clinically diagnosed PLE associated with invasive thymoma or lung cancer are reported. Results Two cases had typical findings in clinical symptoms ( severe neuropsychological deficits, disorientation, memory impairment and seizures) and MRI showed ( abnormal high-signal intensity in hippocampal formations and temporal lobe on T2-weighted imagings) , One patient was investigated by cerebral 18 F-fluoro-2-deoxy-D- glucose- positron emission tomography (FDG-PET) , and highly significant focal hypermetabolism in bilateral temporal and other areas was found. Conclusion The clinical and imaging examination are the improtant method for the diagnosis of PLE. |
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| Keywords: | Paraneoplastic syndrome Limbie encephalitis Clinical features MRI PET |
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