| 肌电图引导局部肌肉注射A型肉毒毒素治疗痉挛性斜颈的疗效观察 |
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| 引用本文： | 姚朝娅,吴婷,李敏,侯熙德. 肌电图引导局部肌肉注射A型肉毒毒素治疗痉挛性斜颈的疗效观察[J]. 临床神经病学杂志, 2011, 24(3) |
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| 作者姓名： | 姚朝娅 吴婷 李敏 侯熙德 |
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| 作者单位： | 南京医科大学第一附属医院神经内科,210029 |
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| 摘 要： | 目的 观察肌电图(EMG)引导局部肌肉注射A型肉毒毒素(BTX-A)治疗痉挛性斜颈(CD)的疗效.方法 应用EMG检查19例CD患者头颈部152块肌肉,针对放松状态下出现的多频群放电位的114块靶肌肉进行BTX-A局部肌肉注射;治疗前后分别采用Tsui量表对病情和疗效进行评估;随访观察疗效持续时间以及不良反应.结果 治疗后EMG发现靶肌肉5块;根据Tsui量表评分,治疗后总有效率第1周为47.3%,第2周为78.9%,第3、4周均为94.7%;随访显示疗效平均保持10个月;不良反应轻微,均在4周内自行缓解.结论 EMG引导局部肌肉注射BTX-A治疗CD安全有效.
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| 关 键 词： | 痉挛性斜颈 A型肉毒毒素 肌电图 |
Observation of the curative effects of local intramuscullar injection with botulinum toxin type A guided by electromyography on treating cervical dystonia |
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| YAO Chao-ya,WU Ting,LI Min,et al.. Observation of the curative effects of local intramuscullar injection with botulinum toxin type A guided by electromyography on treating cervical dystonia[J]. Journal of Clinical Neurology, 2011, 24(3) |
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| Authors: | YAO Chao-ya WU Ting LI Min et al. |
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| Affiliation: | YAO Chao-ya,WU Ting,LI Min,et al.Department of Neurology,the First Affiliated Hospital of Nanjing Medical University,Nanjing 210029,China |
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| Abstract: | Objective To observe the curative effect of local intramuscular injection(IM) with botulinum toxin type A(BTX-A) guided by electromyography(EMG) on treating cervical dystonia(CD).Methods A total of 152 head and neck muscles in 19 CD patients were examined by EMG and 114 targeted-muscles which presented mul-frequence discharged electric potential were found out and locally IM with BTX-A.The pathogenesis condition and curative effect were evaluated before and after IM by Tsui scale,follow-up to observe the ef... |
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| Keywords: | cervical dystonia botulinum toxin type A electromyography |
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