| 思瑞康与利培酮治疗精神分裂症对照研究 |
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| 引用本文： | 王美娟,刘敏,卢玲,胡君,傅秀芹.思瑞康与利培酮治疗精神分裂症对照研究[J].临床精神医学杂志,2000,10(4):200-201. |
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| 作者姓名： | 王美娟 刘敏 卢玲 胡君 傅秀芹 |
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| 作者单位： | 1. 110168,沈阳市精神卫生中心
2. 沈阳医学院临床二院 |
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| 摘 要： | 目的：探讨思瑞康治疗精神分裂症的疗效及副反应。方法：以思康与利培酮治疗精神分裂症各２０例作对照研究，采用阳性症状与阴性症状量表（ＰＡＮＳＳ）、不良反应症状量表（ＴＥＳＳ）评定疗效及副反应。结果：利培酮组有效率８０％，显效率４０％；思瑞康组有效率８９％，显效率７８％。均无明显锥外系反应，仅表现为兴奋激越等副反应。结论：该两种药对治疗精神分裂症均有确切疗效，且安全性相对高，思瑞康对症状的改善可能更好。
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| 关 键 词： | 思瑞康 利培酮 精神分裂症 治疗 |
A controlled study on seroquel and risperidone in the treatment of schizophrenic patients |
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| Wang Meijuan,Liu Min,Lu Ling,.Centre of Mental Health of Shengyang,Liaoning.A controlled study on seroquel and risperidone in the treatment of schizophrenic patients[J].Journal of Clinical Psychological Medicine,2000,10(4):200-201. |
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| Authors: | Wang Meijuan Liu Min Lu Ling Centre of Mental Health of Shengyang Liaoning |
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| Institution: | Wang Meijuan,Liu Min,Lu Ling,.Centre of Mental Health of Shengyang,Liaoning 110168 |
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| Abstract: | Objective:To research the therapeutic and side effects of seroquel in the treatment of schizophrenic patients. Method:Twenty schizophrenic patients were treated with risperidone as the controlled group.The efficacy was measured with the positive and negative symptoms scale (PANSS),while the adverse events were determined by the treatment emergent symptoms scale (TESS). Results:The efficacy rate of risperidone was 80%,in which 40% were improved markedly. The efficacy rate of seroquel was 89%, in which 78% were improved markedly. Conclusion:It is suggested that both drugs are effective exactly in the treatment of schizophrenic patients and fewer side effects.Seroquel appears to be more effective in improving psychiatric symptoms. |
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| Keywords: | Seroquel Risperidone Schizophrenia |
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