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新型非典型抗精神病药:鲁拉西酮
引用本文:陈俊,方贻儒.新型非典型抗精神病药:鲁拉西酮[J].临床精神医学杂志,2022(1):81-84.
作者姓名:陈俊  方贻儒
作者单位:上海交通大学医学院附属精神卫生中心临床研究中心
基金项目:国家自然科学基金国际(地区)合作与交流项目(81761128032);上海申康医院发展中心临床创新三年行动计划(SHDC12020126);深圳市“医疗卫生三名工程”(SZSM201612006);广东省重点领域研发计划(2018B030334001)。
摘    要:精神分裂症和双相障碍是两大常见的重性精神障碍,约占我国精神科住院患者的一半以上,给社会以及患者和家属带来严重的负担.尽管目前有多种非典型抗精神病药可用于治疗这两类精神障碍,但可多维度改善患者症状、且安全性好的药物仍然是目前临床实践中未被满足的需求.鲁拉西酮是一种新近进入中国的新型非典型抗精神病药,在国外可用于治疗精神分...

关 键 词:非典型抗精神病药  精神分裂症  双相障碍  鲁拉西酮

A novel atypical antipsychotic:Lurasidone
CHEN Jun,FANG Yi-ru.A novel atypical antipsychotic:Lurasidone[J].Journal of Clinical Psychological Medicine,2022(1):81-84.
Authors:CHEN Jun  FANG Yi-ru
Institution:(Clinical Research Center,Shanghai Mental Health Center,Shanghai Jiao Tong University School of Medicine,Shanghai 200030,China)
Abstract:Schizophrenia and bipolar disorder are two common severe mental disorders,accounting for more than half of the inpatients in psychiatric departments in China,and bring a severe burden to patients,their families and society.Although there are a variety of atypical antipsychotics that can be used to treat the two mental disorders,medications that can improve patients'symptoms in multiple dimensions and have good safety are still unmet needs in current clinical practice.Lurasidone is a new type of atypical antipsychotic that has recently entered China.It can be used to treat schizophrenia and bipolar I disorder depressive episodes overseas,but its clinical use in China has just started.Therefore,this paper will review the pharmacological characteristics,clinical efficacy and safety of lurasidone,and provide references for standardized clinical use.
Keywords:atypical antipsychotic  schizophrenia  bipolar disorder  lurasidone
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