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西酞普兰治疗抑郁症临床观察
引用本文:王进良,刘晓伟,杨国平,曹磊明,许文龙.西酞普兰治疗抑郁症临床观察[J].临床精神医学杂志,2004,14(1):16-17.
作者姓名:王进良  刘晓伟  杨国平  曹磊明  许文龙
作者单位:214151,江苏无锡市精神卫生中心
摘    要:目的:评价西酞普兰治疗抑郁症的疗效和不良反应。方法:84例抑郁症患者,随机平分为两组,分别给予西酞普兰和阿米替林治疗,疗程8周。用汉密顿抑郁量表(HAMD)、临床疗效总评量表病情严重程度(CGI—SI)和副反应量表(TESS)评定疗效和不良反应结果:西酞普兰与阿米替林对抑郁症疗效相仿,但前者起效快,不良反应少于后者。结论:西酞普兰是一种安全有效的抗抑郁药。

关 键 词:西酞普兰  阿米替林  抑郁症
文章编号:1005-3220(2004)01-0016-02
修稿时间:2003年5月15日

A study of citalopram in the treatment of depression
WANG Jin-liang,LIU Xiao-wei,YANG Guo-ping,et al..A study of citalopram in the treatment of depression[J].Journal of Clinical Psychological Medicine,2004,14(1):16-17.
Authors:WANG Jin-liang  LIU Xiao-wei  YANG Guo-ping  
Institution:WANG Jin-liang,LIU Xiao-wei,YANG Guo-ping,et al.Wuxi Mental Health Center,Jiangsu 214151
Abstract:Objective:To compare the efficacy and side effects of citalopram in the treatment of depression. Method: 84 inpatients and outpatients with depression were randomly assigned to citalopram group and amitriptyline group for 8 weeks.Effects and side reactions were evaluated with HAMD,CGI-SI and TESS before and after the treatment. Results:Findings indicated that the efficacy of citalopram was similar to that of amitriptyline,however citalopram took effect more quickly and its side effects were less than amitriptyline. Conclusion:Citalopram is an effective and safe antidepressant.
Keywords:Citalopram  Amitriptyline  Depression  
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