缓解期双相情感性精神障碍患者认知功能

目的:了解缓解期双相情感性精神障碍患者认知功能损害的特点。方法:采用逻辑记忆、视觉再生记忆、连线测验A和B、数字广度测验、威斯康星卡片分类测验(WCST)及字色混淆测验(stroop)对62例缓解期双相情感性精神障碍患者(患者组)和62名健康者(对照组)进行有关言语学习和记忆、非言语学习和记忆、注意以及执行功能的神经心理学评定,比较两组间认知功能的差异。结果:患者组在即刻逻辑记忆、延迟逻辑记忆、连线测验A和B、WCST正确应答数、完成分类数、持续性错误数以及Stroop C-W操作分上均显著低于对照组(P<0.05~0.01)。结论:双相情感性精神障碍患者的认知缺陷有其特点。

Cognitive function in remitted patients with bipolar affective mental disorder

Objective:To understand the cognitive function impairment in remitted patients with bipolar affective mental disorder.Method:Verbal learning and memory,nonverbal learning and memory,attention and executive function were assessed respectively with logical memory,visual reproduction,trail making test A and B,digit span subtest,WCST and stroop test in 62 remitted patients with bipolar affective mental disorder and 62 normal controls. Results:The perfornance of the patients on logical memory,trail making test A and B,WCST caregories,WCST correct,WCST perseveative errors and stroop C-W was significantly worse than those of normal controls(P<0.05 or 0.01).Conclusion:Cognitive deficits in remitted patients with bipolar affective mental disorder have some peculiarity.