| 西酞普兰与氟西汀治疗恶劣心境对照研究 |
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| 引用本文： | 李祥仁,周爱华,汤玲,朱国奎.西酞普兰与氟西汀治疗恶劣心境对照研究[J].临床精神医学杂志,2008,18(3):186-187. |
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| 作者姓名： | 李祥仁 周爱华 汤玲 朱国奎 |
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| 作者单位： | 江苏盐城第四人民医院,224003 |
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| 摘 要： | 目的：探讨西酞普兰与氟西汀治疗恶劣心境的疗效和安全性。方法：将116例恶劣心境患者随机分为西酞普兰组和氟西汀组，治疗6周，用汉密尔顿抑郁量表（HAMD）和治疗中出现的症状量表（TESS）评定疗效和不良反应。结果：西酞普兰组和氟西汀组总体疗效相当，西酞普兰起效较快，不良反应较轻。结论：西酞普兰治疗恶劣心境既有效又安全。
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| 关 键 词： | 西酞普兰 氟西汀 恶劣心境 |
Comparative study on the treatment of dysthymia between citalopram and fluoxetine |
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| LI Xian-gren,ZHOU Ai-hua,TANG Ling,ZHU Guo-kui.Comparative study on the treatment of dysthymia between citalopram and fluoxetine[J].Journal of Clinical Psychological Medicine,2008,18(3):186-187. |
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| Authors: | LI Xian-gren ZHOU Ai-hua TANG Ling ZHU Guo-kui |
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| Institution: | LI Xiang-ren, ZHOU Ai-hna, TANG-Ling,ZHU Guo-kui(The Fouth People＇ s Hospital of Yancheng, Yancheng 224003, China) |
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| Abstract: | Objective:To compare the efficacy and adverse effects between citalopram and flouxetine in the treatment of dysthymia. Method:116 patients with dysthymia were randomly assigned to citalopram group and fluoxetine group for six weeks.The clinical efficacy was evaluated by hamilton rating scale for depression(HAMD)and the adverse effects were estimated by treatment emergent symptoms scale(TESS). Results:There was no significant difference in the efficacy between the two groups,with rapid efficacy and milder adverse effects for patients in citalopram group. Conclusion: Citlopram is an effective and safe antidepressant in the treatment of dysthymia. |
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| Keywords: | citalopram flouxetine dysthymia |
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