首页 | 本学科首页   官方微博 | 高级检索  
检索        

长期服用抗精神病药对脂肪酸与血糖的影响
引用本文:孙静,张志珺,王丛杰,张晓斌,王筱兰,尚晓芳,朱荣鑫.长期服用抗精神病药对脂肪酸与血糖的影响[J].临床精神医学杂志,2004,14(5):259-261.
作者姓名:孙静  张志珺  王丛杰  张晓斌  王筱兰  尚晓芳  朱荣鑫
作者单位:1. 210029,南京医科大学
2. 南京医科大学附属脑科医院精神科
3. 江苏淮安市第三人民医院
4. 江苏扬州五台山医院
摘    要:目的 :研究慢性精神分裂症患者长期服用抗精神病药物与空腹游离脂肪酸及空腹血糖的关系。 方法 :2 18例病程 >5年的慢性精神分裂症患者接受糖尿病流行病学调查 ,测定空腹血糖、餐后2h血糖及空腹游离脂肪酸。 结果 :糖尿病组空腹游离脂肪酸水平显著高于血糖正常组 ;相关分析显示 2 18例患者空腹游离脂肪酸与空腹血糖呈显著正相关 ;糖尿病组、血糖调节异常组 2项指标间无显著相关性 ;血糖正常组空腹游离脂肪酸与空腹血糖呈显著正相关。 结论 :长期服用抗精神病药可导致部分患者游离脂肪酸及血糖处于平衡失调状态

关 键 词:精神分裂症  游离脂肪酸  血糖  抗精神病药
文章编号:1005-3220(2004)05-0259-03
修稿时间:2004年5月12日

To study the association between plasma fasting free fatty acids and fasting plasma glucose in patients treated with psychotics for a long period of time
SUN Jing,ZHANG Zhi-jun,WANG Cong-jie,et al..To study the association between plasma fasting free fatty acids and fasting plasma glucose in patients treated with psychotics for a long period of time[J].Journal of Clinical Psychological Medicine,2004,14(5):259-261.
Authors:SUN Jing  ZHANG Zhi-jun  WANG Cong-jie  
Institution:SUN Jing,ZHANG Zhi-jun,WANG Cong-jie,et al.Department of Psychiatry,Affiliated Brain Hospital of Nanjing Medical University,Nanjing 210029
Abstract:Objective:To investigate the association between fasting plasma free fatty acids and fasting plasma glucose in patients with chronic schizophrenia who had taken antipsychotics for a long period of time. Method:Fasting plasma glucose,2-hour post-meal plasma glucose and fasting plasma free fatty acids were measured in 218 patients with chronic schizophrenia whose natural courses were more than 5 years.According to the level of plasma glucose,these patients were divided into three groups:diabetes mellitus group, abnormal regulating glucose group and normal glucose group. Results:As compared to normal glucose group,patients in diabetes mellitus group had significantly higher plasma levels of fasting free fatty acids.However,the plasma level of fasting free fatty acids was significantly correlated with the level of fasting plasma glucose only in the normal glucose group. Conclusion:There is equilibrium maladjustment between plasma free fatty acids and plasma glucose in some of those patients who had taken antipsychotics for a long period of time.
Keywords:Schizophrenia  Plasma free fatty acids  Plasma glucose  Antipsychotics
本文献已被 CNKI 万方数据 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号