| 曲唑酮与阿米替林治疗抑郁症对照研究 |
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| 引用本文： | 杨建章,郭振宇,宋丽.曲唑酮与阿米替林治疗抑郁症对照研究[J].临床精神医学杂志,2006,16(2):90-91. |
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| 作者姓名： | 杨建章 郭振宇 宋丽 |
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| 作者单位： | 463000,河南驻马店市精神病医院 |
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| 摘 要： | 目的:探讨曲唑酮对抑郁症的疗效。方法:将80例患者随机平分为两组,分别给予曲唑酮和阿米替林治疗,疗程4周。用汉密尔顿抑郁量表(HAMD)和副反应量表(TESS)评定疗效和不良反应。结果:治疗4周后,两药对抑郁症均有良好疗效,疗效近似(P>0.05);但曲唑酮不良反应小,程度轻(P<0.05或P<0.01)。结论:曲唑酮治疗抑郁症安全,疗效确切。
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| 关 键 词： | 抑郁症 曲唑酮 阿米替林 |
| 文章编号： | 1005-3220（2006）02-0090-02 |
| 收稿时间： | 2005-05-30 |
| 修稿时间： | 2005年5月30日 |
Controlled study of trazodone and amitriptylin in treatment of depression |
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| YANG Jian-zhang,GUO Zhen-yu,SONG Li.Controlled study of trazodone and amitriptylin in treatment of depression[J].Journal of Clinical Psychological Medicine,2006,16(2):90-91. |
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| Authors: | YANG Jian-zhang GUO Zhen-yu SONG Li |
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| Institution: | Zhumadian Mental Hospital of Henan Province,Zhumadian 463000, China |
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| Abstract: | Objective:To explore the efficacy of trazodone in the treatment of depression.Method:80 depressive patients were randomly divided into two groups.40 patients were treated with trazodone and others were treated with amitriptylin for 4 weeks.The therapeutic response and side effects were evaluated with the HAMD and TESS.Results:Trazodone and amitriptylin showed good effect in the treatment of depression,trazodone had similar efficacy to amitriptylin,and there were not significant difference between the two groups(P>0.05);but side effects of trazodone were less and milder(P<0.05 or P<0.01).Conclusion:Trazodone is a safe,reliable effect in the treatment of depression. |
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| Keywords: | depression trazodone amitriptylin |
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