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| 奥氮平与氯氮平治疗精神分裂症临床对照观察 | |
| 引用本文： | 肖勃,谢文娇,丘春柳,林坚,郭文璇,邱开封.奥氮平与氯氮平治疗精神分裂症临床对照观察[J].临床精神医学杂志,2009,19(2). |
| 作者姓名： | 肖勃 谢文娇 丘春柳 林坚 郭文璇 邱开封 |
| 作者单位： | 1. 汕头大学精神卫生中心,515063 2. 汕头大学医学院第一附属医院 3. 汕头市金平区第一中医医院 4. 汕头大学医学院第二附属医院 |
| 基金项目： | 广东汕头市重点科技计划项目(汕府科[2006]82) |
| 摘 要： | 目的:探讨国产奥氮平治疗精神分裂症的临床疗效及其对生活质量的影响。方法:将64例精神分裂症患者随机分为奥氮平组和氯氮平组治疗8周,于治疗前后用阳性与阴性症状量表(PAN-SS)和治疗中出现的症状量表(TESS)评定其疗效和不良反应,生活质量量表(GQOLI-74)分析患者的生活质量。结果:奥氮平组与氯氮平组疗效差异无显著性(P>0.05);奥氮平组生活质量各维度改善均优于氯氮平组。结论:国产奥氮平和氯氮平对于精神分裂症的疗效相当,对提高精神分裂症患者的生活质量明显优于氯氮平。 |
| 关 键 词： | 精神分裂症 奥氮平 氯氮平 生活质量 |
A controlled study between olanzapine and clozapine in the treatment of schizophrenia |
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| XIAO Bo,XIE Wen-jiao,QIU Chun-liu,LIN Jian,GUO Wen-xuan,QIU Kai-feng.A controlled study between olanzapine and clozapine in the treatment of schizophrenia[J].Journal of Clinical Psychological Medicine,2009,19(2). | |
| Authors: | XIAO Bo XIE Wen-jiao QIU Chun-liu LIN Jian GUO Wen-xuan QIU Kai-feng |
| Institution: | XIAO Bo,XIE Wen-jiao,QIU Chun-liu,LIN Jian,GUO Wen-xuan,QIU Kai-feng.Mental Health Center of Shantou University Medical College,Shantou 515063,China |
| Abstract: | Objective:To study the influence of domestic olanzapine on clinical efficacy and quality of life. Method:64 patients with schizophrenia were randomly divided into olanzapine group and clozapine group for 8 weeks.The efficacy and adverse effects were evaluated with positive and negative syndrome scale(PANSS)and treatment emergent symptoms scale(TESS).The quality of life of patients with schizophrenia was accessed by General Quality of Life Inventory(GQOLI-74). Results:There was no significant difference in c... |
| Keywords: | schizophrenia olanzapine clozapine quality of life |
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