| 新型抗精神病药对血糖水平影响的比较研究 |
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| 引用本文： | 赵庆莲,许从芳.新型抗精神病药对血糖水平影响的比较研究[J].山东精神医学,2004,17(1):1-2. |
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| 作者姓名： | 赵庆莲 许从芳 |
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| 作者单位： | 山东省济宁市精神病防治院
272051(赵庆莲)，山东省济宁市精神病防治院 272051(许从芳) |
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| 摘 要： | 目的 比较几种新型抗精神病药对血糖水平的影响。方法 前瞻性调查使用新型抗精神病药治疗的住院精神病人 ,观察血糖变化 ,并分析影响血糖水平的相关因素 (年龄、病程、药物种类、药物剂量等 )。结果 在 12 0例住院精神病人中 ,氯氮平、奥氮平、利培酮和奎的平 4种抗精神病药引起糖代谢异常的机率有显著性差异 (P <0 .0 5 )。年龄越大引起糖代谢异常的机率越高 (P <0 .0 5 )。结论 氯氮平、奥氮平比利培酮、奎的平引起糖代谢异常的发生率高 ,奎的平最低 ,应引起临床关注
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| 关 键 词： | 抗精神病药 血糖 精神病 住院患者 糖代谢异常 |
| 文章编号： | 1009-7201(2004)-01-0001-02 |
| 修稿时间： | 2002年11月21 |
The effect of new antipsychotics on glucose metabolism |
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| Zhao Qinglian,Xu Congfang.The effect of new antipsychotics on glucose metabolism[J].Shangdong Archives of Psychiatry,2004,17(1):1-2. |
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| Authors: | Zhao Qinglian Xu Congfang |
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| Institution: | Zhao Qinglian,Xu Congfang.Jining Mental Hospital,Shandong 272051,China |
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| Abstract: | Objective To explore the effect of new antipsychotics on glucose metabolism.Methods Data of blood glucose changing were pretrospectively collected from 120 inpatients treated with new antipsychatics,and relative factors(age,course of diseases,type of the drug,dose)affecting the glucose metabolism were analyzed.Results In 120 inpatients,the incidence of glucose metabolism abnormality showed significant difference among the patients treated with different drugs(P<0.05).Age appeared to increase the risk for glucose metabolism abnormality.Conclusion The incidences of glucose metabolism abnormality and DM in patients treated with clozapine and olanzapine were much higher than those in patients treated with risperdal and quetiapine. |
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| Keywords: | New antipsychotics Glucose metabolism abnormality Diabetes Mellitus(DM) |
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