脑膜血管型神经梅毒病灶侧和对侧核磁共振灌注加权成像特征的研究

目的 研究脑膜血管型神经梅毒的影像学特征,指导与脑梗死的鉴别诊断.方法 对神经梅毒患者进行头部MRI平扫+增强、磁共振血管成像(Magnetic Resonance Angiography,MRA)、灌注加权成像(perfusion weighted imaging,PWI)和磁敏感加权成像(Susceptibilit...

Study on the characteristics of MRI perfusion weighted imaging in the focal side and contralateral side of meningeal vascular neurosyphilis

Objective The author studied the imaging features of meningeal vascular neurosyphilis,and provided guidance for the differential diagnosis of cerebral infarction.Methods Patients with meningeal vascular syphilis underwent head MRI plain scan+enhancement,PWI,MRA and SWI.The four parameters of PWI on the side of the lesion were compared with those on the contralateral side of the lesion.Results A total of 7 patients with neurosyphilis underwent head MRI examination,and a total of 9 responsible lesions were found.They are listed as follows,two pontine lesions,one radiative coronary lesion,one thalamic lesion,one occipital lobe lesion,two parietal lobe lesions,one insular lobe lesion,and one frontal lobe lesion.The edge of the lesion in a radiating crown is enhanced.Through MRA examination,6 patients were found to have vascular stenosis.PWI examination of patients with neurosyphilis found that compared with the contralateral side,the rCBV value(72.47±46.51)vs.(130.68±38.92)]of the responsible lesion area decreased,t=4.172,P=0.002;and the rCBF value(111.10±37.89)vs.(153.43±50.81)]also decreased,t=2.804,P=0.025.Conclusion The PWI manifestations of intracranial lesions in patients with neurosyphilis may have different imaging features from cerebral infarction.