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创伤后应激障碍的中枢神经系统机制
引用本文:刘媛,王正国,伍亚民.创伤后应激障碍的中枢神经系统机制[J].中国临床神经科学,2008,16(4):442-446.
作者姓名:刘媛  王正国  伍亚民
作者单位:1. 第三军医大学大坪医院野战外科研究所三室
2. 创伤、烧伤与复合伤国家重点实验室 400042
摘    要:创伤后应激障碍(PTSD)所表现的各种精神症状,是与中枢神经系统(CNS)对应激信息的记忆密切相关的,本文就创伤后CNS的突触可塑性、CNS内神经递质的变化、PTSD的神经解剖学基础及改变、丘脑-垂体-肾上腺轴功能和PTSD治疗等方面对PTSD发生的中枢神经机制进行阐述。

关 键 词:创伤后应激障碍  中枢神经系统  机制

The Central Nervous Mechanism of Post-trauma Stress Disorder
LIU Yuan WANG Zheng-Guo WU Ya-Min The rd.The Central Nervous Mechanism of Post-trauma Stress Disorder[J].Chinese Journal of Clinical Neurosciences,2008,16(4):442-446.
Authors:LIU Yuan WANG Zheng-Guo WU Ya-Min The rd
Institution:LIU Yuan WANG Zheng-Guo WU Ya-Min The 3rd Department of Research Institute of Surgery,Daping Hospital,the Third Military Medical University,State Key Laboratory of Trauma,Burns and Combined Injury,Chongqing 400042,China
Abstract:The symptoms after post-trauma stress disorder(PTSD) are closely related to the stress memory of central nervous system.In this paper,we review the central nervous mechanism of PTSD as followed in the five aspects: the plasticity of synapses,the change of neurotransmitters,the bases of nervous anatomy, function of HPA axis and the treatment of PTSD.
Keywords:post-trauma stress disorder  central nervous system  mechanism
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