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脑血栓形成合并阻塞性睡眠呼吸暂停综合征对认知和神经功能障碍的影响
引用本文:任蕾,王凯,杜井波,李珍,李庆云.脑血栓形成合并阻塞性睡眠呼吸暂停综合征对认知和神经功能障碍的影响[J].中国临床神经科学,2009,17(4):392-395.
作者姓名:任蕾  王凯  杜井波  李珍  李庆云
作者单位:1. 上海市静安区老年医院呼吸科,200042
2. 上海交通大学医学院附属瑞金医院呼吸科,200025
基金项目:上海市静安区十、百、千人才培养计划 
摘    要:目的:探讨脑血栓形成患者合并阻塞性睡眠呼吸暂停低通气综合征(OSAHS)对认知和神经功能障碍的影响。方法:对46例脑血栓形成患者及8例单纯OSAHS患者采用多导睡眠图(PSG)检测,并行简易精神状态检查(MMSE)评分、中国神经功能缺损评定量表及欧洲脑卒中量表评分,进一步对相关结果进行对比分析。结果:脑血栓形成合并OSAHS组睡眠呼吸暂停低通气指数(AHI)显著高于单纯脑血栓形成组(P〈0.05)。脑血栓形成合并OSAHS的患者MMSE评分、中国神经功能缺损评定量表及欧洲脑卒中量表评分较单纯OSAHS及单纯脑血栓形成患者差异有显著统计学意义(P〈0.01)。脑血栓形成合并OSAHS组AHI与MMSE及欧洲脑卒中量表评分呈负相关。结论:脑血栓形成合并OSAHS患者的认知功能及神经功能下降。

关 键 词:脑血栓形成  阻塞性睡眠呼吸暂停综合征  认知  呼吸暂停  低通气指数  多导睡眠图

Influence on Cognitive and Neurological Function of Patients of Cerebral Thrombosis Combined with Obstructive Sleep Apnea Hypopnea Syndrome
REN Lei,WANG Kai,DU Jing-Bo,LI Zhen,LI Qing-Yun.Influence on Cognitive and Neurological Function of Patients of Cerebral Thrombosis Combined with Obstructive Sleep Apnea Hypopnea Syndrome[J].Chinese Journal of Clinical Neurosciences,2009,17(4):392-395.
Authors:REN Lei  WANG Kai  DU Jing-Bo  LI Zhen  LI Qing-Yun
Institution:REN Lei, WANG Kai, DU Jing-Bo, LI Zhen, LI Qing- Yun(1.Department of Respiratory Medicine, 2Department of Rehabilitation Medicine, Shanghai Jingan Geriatric Hospital, 200042; 3Department of Respiratory Medicine, Ruijin Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200025, China.)
Abstract:Aim: To investigate the influence on cognitive and neurological function of patients of cerebral thrombosis combined with obstructive sleep apnea hypopnea syndrome(OSAHS). Methods: 46 patients with cerebral thrombosis and 8 patients with OSAHS were tested by polysomnography(PSG). Mini-Mental State Examination(MMSE), Chinese Neurological Impairment Scale and European Stroke Scale were recorded and the relationship with AHI were analyzed. Results: The score of MMSE, Chinese Neurological Impairment Scale and European Stroke Scale in patients with cerebral thrombosis combined with OSAHS are significantly lower than those of simple cerebral thrombosis or simple OSAHS. AHI of patients with cerebral thrombosis combined with OSAHS are negative correlation with the score of MMSE and European Stroke Scale. Conclusion: Combining with OSAHS has influence on cognitive and neurological function of patients with cerebral thrombosis.
Keywords:cerebral thrombosis  obstructive sleep apnea syndrome  cognition  apnea  hypopneaindex  polysomnography
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