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胰岛素样生长因子-1与阿尔茨海默病关系研究进展
引用本文:赵弘轶,赵忠新,黄流清.胰岛素样生长因子-1与阿尔茨海默病关系研究进展[J].中国临床神经科学,2011,19(5):534-538.
作者姓名:赵弘轶  赵忠新  黄流清
作者单位:上海市长征医院神经内科,200003
基金项目:上海市科学技术委员会资助课题
摘    要:胰岛素样生长因子-1(IGF-1)在神经营养方面的作用为人所熟悉。近年的研究发现,IGF-1与阿尔茨海默病(AD)以及认知功能关系密切。本研究就IGF-1在体内的分布、与AD的关系,以及影响AD可能的机制等方面,对其发挥的主要作用进行综述。

关 键 词:胰岛素样生长因子-1  阿尔茨海默病  神经营养

Advances in the Relationship of Insulin-like Growth Factor-1 and Alzheimer's Disease
ZHAO Hong-Yi,ZHAO Zhong-Xin,HUANG Liu-Qing.Advances in the Relationship of Insulin-like Growth Factor-1 and Alzheimer's Disease[J].Chinese Journal of Clinical Neurosciences,2011,19(5):534-538.
Authors:ZHAO Hong-Yi  ZHAO Zhong-Xin  HUANG Liu-Qing
Institution:ZHAO Hong-Yi,ZHAO Zhong-Xin,HUANG Liu-Qing Department of Neurology,Affiliated Changzheng Hospital of the Second Military Medical University,Shanghai 200003,China
Abstract:Insulin-like growth factor-1(IGF-1) has been widely recognized as its neurotrophic function.In recent studies,researchers found IGF-1 have a close relationship with Alzheimer's disease,with cognitive function.Distribution of IGF-1 and its association with AD,as well as the possible mechanism were reviewed.
Keywords:insulin-like growth factor-1  Alzhemier's disease  neurotrophy  
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