Behavioral Side Effects of Gabapentin in Children |
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Authors: | D O Lee R J Steingard M Cesena S L Helmers† J J Riviello† M A Mikati† |
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Institution: | Department of Child and Adolescent Psychiatry, Emory University School of Medicine, Atlanta, Georgia, U.S.A.;Department of Psychiatry, Harvard Medical School, Children's Hospital, Boston, Massachusetts, U.S.A.;Department of Neurology, Harvard Medical School, Children's Hospital, Boston, Massachusetts, U.S.A. |
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Abstract: | Summary: We report 7 children who received gabapentin (GBP) as adjunctive medication and subsequently developed behavioral side effects. These behavioral changes consisted of intensification of baseline behaviors as well as new behavioral problems. Behaviors that parents considered most troublesome were tantrums, aggression directed toward others, hyperactivity, and defiance. All behavioral changes were reversible and were managed by dose reduction or discontinuation of GBP. All children had baseline attention deficit hyperactivity disorder and developmental delays. |
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Keywords: | Gabapentin Attention deficit with hyperactivity Adverse effects Child behavior |
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