Pre- and Postoperative Auditory Event-Related Potentials in Temporal Lobe Epilepsy |
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Authors: | Esa Mervaala Unto Nousiainen Jukka Kinnunen Matti Vapalahti Paavo Riekkinen† |
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Institution: | Department of Clinical Neurophysiology, Vaajasalo Hospital, Kuopio, Finland. |
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Abstract: | We studied auditory event-related potentials (ERPs) in 11 surgically treated patients with intractable temporal lobe epilepsy (TLE) pre- and postoperatively. ERPs through sphenoidal electrodes (Sp1-T3, Sp2-T4) provided clinically relevant and correctly lateralizing electrophysiologic evidence of temporal lobe dysfunction in 9 of 11 patients, confirmed by EEGs, electrocorticograms, neuroradiologic, and neuropsychological results, and clinical follow-up. Lateralizing asymmetries were noted in P300 amplitude, but latencies were prolonged bilaterally. Sphenoidal ERPs might serve as a new functional indicator of temporal lobe dysfunction in patients evaluated for epilepsy surgery. |
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Keywords: | Neurosurgery Auditory evoked potentials Complex partial seizures-Temporal lobe epilepsy |
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