N,N dimethylglycine and epilepsy |
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Authors: | G Gascon B Patterson K Yearwood H Slotnick |
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Institution: | Department of Neuroscience, University of North Dakota School of Medicine, Fargo. |
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Abstract: | Nineteen institutionalized patients with frequent seizures (group average two to three per day; seizure types--generalized, akinetic/myoclonic), were treated randomly with either placebo or N,N dimethylglycine (DMG) for 28 days. Dosage was 300 mg/day for the first 14 days and then 600 mg/day. Plasma levels were measured at baseline, days 2, 5, 8, 15, 22, 30, and 1 and 2 weeks after the study ended. No differences in seizure frequency were noted between placebo and DMG or between baseline and test conditions. No toxicity was noted. |
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Keywords: | Anticonvulsants N N dimethylglycine Sulfur amino acids |
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