Thrombolysis for stroke caused by infective endocarditis: an illustrative case and review of the literature |
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Authors: | Elodie Ong Laura Mechtouff Emilien Bernard Tae-Hee Cho Lansana Laho Diallo Norbert Nighoghossian Laurent Derex |
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Institution: | 1. Stroke Unit, Neurology Department, Neurological Hospital, Lyon, 59, boulevard Pinel, 69677, Bron Cedex, France
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Abstract: | Infective endocarditis represents a classical contra-indication to thrombolysis for acute ischemic stroke due to a potential increased risk of intracranial hemorrhage. However, some case reports have suggested safety and potential efficacy of intravenous or intra-arterial thrombolysis in stroke related to infective endocarditis. We present a case of ischemic stroke related to infective endocarditis who was treated with intravenous tissue plasminogen activator within the first 3 h of symptoms onset and subsequently developed symptomatic multifocal intracerebral hemorrhages, and summarize currently available data on this issue. |
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