Facial palsy in multiple sclerosis |
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Authors: | T Fukazawa F Moriwaka K Hamada T Hamada K Tashiro |
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Institution: | (1) Hokuyukai Neurology Hospital, Niju yon ken 2-2-4-30, Nishi-ku, Sapporo 063, Japan Tel.: 81-11-631-1161, Fax: 81-11-631-1163, JP;(2) Department of Neurology, Hokkaido University School of Medicine, Sapporo 060, Japan Tel.: 81-11-716-1161 ext. 6028, Fax: 81-11-700-5356, JP |
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Abstract: | Facial palsy occurred in 21 (19.6%) of 107 Japanese patients with multiple sclerosis (MS) during a mean follow-up period
of 4.3 years. We observed residual signs of facial palsy in five other patients in whom acute onset was confirmed from medical
records. Facial palsy began on average 7.6 years after the onset of MS but in five patients (4.7%) was the first symptom of
MS, preceding the next MS symptom by 0.5–3 years. Facial palsy was usually associated with other brainstem signs, while two
patients showed only facial palsy 1 and 3 years after the onset of MS. Twenty-one (84.0%) of the 25 patients who underwent
brain magnetic resonance imaging (MRI) showed brainstem lesions in the pontine tegmentum ipsilateral to the facial palsy.
However, the two patients without other symptoms or signs had no apparent causal lesion on MRI, which suggests difficulty
in differentiating idiopathic Bell’s palsy from MS- associated facial palsy by MRI, although it has an excellent capacity
to detect causal lesions of facial palsy associated with MS.
Received: 6 March 1997 Received in revised form: 25 July 1997 Accepted: 12 August 1997 |
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Keywords: | Multiple sclerosis Facial palsy Magnetic resonance imaging |
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