福建省精神障碍流行病学调查

目的 了解福建省年龄≥15岁人群各类精神障碍的患病率、分布特点和规律,为制定全省精神卫生规划提供科学依据.方法 2009年2-6月,采用多阶段分层整群随机抽样方法,抽取10个县(市)中1万名年龄≥15岁的个体为调查对象,先由护士用扩展的一般健康问卷12项将调查对象分为患精神疾病高危险人群、中危险人群、低危险人群,然后由精神科医生以美国精神障碍诊断与统计手册第4版(DSM-IV)轴I障碍临床定式检查患者版,依次对100%高危险人群、40%中危险人群、10%低危险人群进行调查,使用DSM-IV对各类精神障碍进行诊断.结果 (1)共有9986人完成调查,精神障碍的总时点患病率为17.44%(95%可信区间为16.70%～18.19%);最常见的特定精神障碍为重性抑郁障碍(major depressive disorder,3.35%)、酒精依赖性和滥用性障碍(2.93%)、未特定抑郁障碍(2.29%).(2)女性精神障碍总时点患病率高于男性(17.60%vs 17.32%),差异有统计学意义(P<0.05);农村精神障碍总时点患病率与城市之间的差异无统计学意义(17.72%vs17.01%,P>0.05).结论 福建省精神障碍患病率较高,女性高于男性,其中重性抑郁障碍、酒精依赖性和滥用性障碍以及未特定抑郁障碍是我省最常见的精神障碍;加强对常见精神障碍的防治,关注女性精神障碍患者,应成为福建省精神卫生工作的重点.

Abstract：

Objective To determine the prevalence and distribution of mental disorders in adults 15 years of age and older in Fujian province.Methods From Feb.2009 to June 2009,stratified multistage cluster randomization sampling was used to identify 10 000 individuals≥15 years of age from 10 counties (cities).Subjects were classified as high,moderate or low risk of having a mental disorder based on assessment with the expanded version of the General Health Questionnaire(GHQ)(as administered by psychiatric nurses),and then psychiatrists determined their diagnoses by administering the Structured Clinical Interview for DSM-IV(SCID)to 100%of the high-,40% of moderate-,and 10% of low-risk subjects.Results Among the 9986 who completed the screening,the prevalence of any current mental disorder wes 17.44%(95% CI:16.70%-18.19%).The current prevalence rates of the most common specific disorders were as follows:3.35%(major depressive disorder),2.93%(alcohol dependence and abuse disorders),2.29%the non-specific(NOS)depressive disorder].(2)The prevalence of any mental disorder was higher in females than in males(17.60%VS.17.32%,P<0.05).There was no significant difference in the prevalence of any mental disorder between urban and rural residents(17.72%vs 17.01%,P>0.05).Conclusions The prevalence of any mental disorders in Fujian province is high,and higher in the female than the male.Major depressive disorder,alcohol dependence and abuse disorders,as well as the non-specific depressive disorder are the most common mental disorders.Strengthening the prevention and treatment of common mental disorders,especially in women,should be the focus of the mental health work in Fujian province.

Epidemiological survey of mental disorder in Fujian province

Objective To determine the prevalence and distribution of mental disorders in adults 15 years of age and older in Fujian province.Methods From Feb.2009 to June 2009,stratified multistage cluster randomization sampling was used to identify 10 000 individuals≥15 years of age from 10 counties (cities).Subjects were classified as high,moderate or low risk of having a mental disorder based on assessment with the expanded version of the General Health Questionnaire(GHQ)(as administered by psychiatric nurses),and then psychiatrists determined their diagnoses by administering the Structured Clinical Interview for DSM-IV(SCID)to 100%of the high-,40% of moderate-,and 10% of low-risk subjects.Results Among the 9986 who completed the screening,the prevalence of any current mental disorder wes 17.44%(95% CI:16.70%-18.19%).The current prevalence rates of the most common specific disorders were as follows:3.35%(major depressive disorder),2.93%(alcohol dependence and abuse disorders),2.29%the non-specific(NOS)depressive disorder].(2)The prevalence of any mental disorder was higher in females than in males(17.60%VS.17.32%,P<0.05).There was no significant difference in the prevalence of any mental disorder between urban and rural residents(17.72%vs 17.01%,P>0.05).Conclusions The prevalence of any mental disorders in Fujian province is high,and higher in the female than the male.Major depressive disorder,alcohol dependence and abuse disorders,as well as the non-specific depressive disorder are the most common mental disorders.Strengthening the prevention and treatment of common mental disorders,especially in women,should be the focus of the mental health work in Fujian province.