抑郁症及其亚型的睡眠脑电图研究

目的 探讨抑郁症患者睡眠脑电图的异常改变以及抑郁闰不同亚型之间的差异。方法 采用日本光电ＲＭ－６０００多导生理记录仪，对１８例抑郁症患者和１９名健康人进行睡眠脑电图检查。结果 与对照组比较，抑郁症组出现明显的醒觉时间增多、睡眠总时间减少、晒起时间增加、睡眠效率下降、睡眠维持率下降、第一阶段睡眠百分比增加、快速眼球运动（ＲＥＭ）潜代期缩短和ＲＥＭ密度增加，经统计学处理差异均有显著性（Ｐ〈０．０５）。

A study on sleep EEG in depression and its subtypes

Objective The purpose of this study was to examine the abnormality of sleep EEG in depression and its various subtypes. Methods A sleep EEG study was carried out in 18 depressive patients and 19 normal controls. Results The depressive patients showed significantly prolonged awake time, reduced total sleep duration, increased early morning awakening, decreased sleep efficiency, reduced sleep maintenance, increased percentage of stage 1 sleep, shortened REM latency and increased REM density. Depressives with psychotic features significantly differed from those without psychotic features in that they had longer awakening duration, shorter total sleeping duration, worse sleeping maintenance, and lower percentage of slow wave sleep. Conclusion It suggests that the early appearance of REM sleep with increased REM activity could be a relatively specific marker in sleep changes in depression, and there are differences in sleep EEG changes between those with psychotic and non psychotic features.