| 不同波形及强度低频电刺激脑缺血大鼠血浆降钙素基因相关肽及神经元特异性烯醇化酶变化无差异 |
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| 引用本文： | 高强,何成奇,Jing He,Shasha Li,Yonghong Yang.不同波形及强度低频电刺激脑缺血大鼠血浆降钙素基因相关肽及神经元特异性烯醇化酶变化无差异[J].中国神经再生研究,2011,6(28):2217-2221. |
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| 作者姓名： | 高强 何成奇 Jing He Shasha Li Yonghong Yang |
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| 作者单位： | 四川大学华西医院康复医学科,四川大学华西医院康复医学科,四川大学华西医院康复医学科,四川大学华西医院康复医学科,四川大学华西医院康复医学科 |
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| 基金项目： | 863项目 (2007AA022Z482) |
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| 摘 要： | Following acute cerebral ischemia in rats,plasma calcitonin gene-related peptide decreased and the level of serum neuron specific enolase and the volume of the infarction increased.Square-wave and triangular-wave electrical stimulation with low or high intensities could increase the plasma calcitonin gene-related peptide,decrease the serum neuron specific enolase and reduce the infarction volume in the brain in rats with cerebral ischemia.There was no significant difference between different wave forms and intensities.The experimental findings indicate that low-frequency electrical stimulation with varying waveforms and intensities can treat acute cerebral ischemia in rats.
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| 关 键 词： | low-frequency electrical stimulation acute cerebral ischemia calcitonin gene-related peptide neuron specific enolase infarction volume |
Changes in plasma calcitonin gene-related peptide and serum neuron specific enolase in rats with acute cerebral ischemia after low-frequency electrical stimulation with different waveforms and intensities |
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| Qiang Gao,Yonghong Yang,Shasha Li,Jing He,Chengqi He.Changes in plasma calcitonin gene-related peptide and serum neuron specific enolase in rats with acute cerebral ischemia after low-frequency electrical stimulation with different waveforms and intensities[J].Neural Regeneration Research,2011,6(28):2217-2221. |
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| Authors: | Qiang Gao Yonghong Yang Shasha Li Jing He Chengqi He |
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| Institution: | Qiang Gao,Yonghong Yang,Shasha Li,Jing He,Chengqi He Department of Rehabilitation Medicine,Key Laboratory of Rehabilitation Medicine of Sichuan Province,West China Hospital,Sichuan University,Chengdu 610041,Sichuan Province,China |
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| Abstract: | Following acute cerebral ischemia in rats, plasma calcitonin gene-related peptide decreased and the level of serum neuron specific enolase and the volume of the infarction increased. Square-wave and triangular-wave electrical stimulation with low or high intensities could increase the plasma calcitonin gene-related peptide, decrease the serum neuron specific enolase and reduce the infarction volume in the brain in rats with cerebral ischemia. There was no significant difference between different wave forms and intensities. The experimental findings indicate that low-frequency electrical stimulation with varying waveforms and intensities can treat acute cerebral ischemia in rats. |
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| Keywords: | low-frequency electrical stimulation acute cerebral ischemia calcitonin gene-related peptide neuron specific enolase infarction volume |
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