贵阳地区成人骨密度与骨质疏松症调查*

背景：中国很多地方做过骨密度的变化规律及骨质疏松症的调查，但对于地处西部的贵阳地区，尚缺乏对的骨密度变化规律和骨质疏松症全面系统的随机调查。 目的：调查贵阳地区成人骨密度，为该地区骨质疏松的预防、诊断、治疗提供参考依据。 方法：2008/2011用双能X射线骨密度仪对贵阳地区共1 334例年龄为20~79岁的人群进行骨密度测定，测定部位包括腰椎1~4椎体、右股骨近端，以峰值骨密度减低2. 0 SD为诊断骨质疏松症标准，按性别、10岁一个年龄分组进行统计学分析。 结果与结论：贵阳地区男、女骨密度峰值均在20~29岁年龄组，女性50岁、男性60岁以后骨密度值明显降低。20~29岁的女性人群中出现骨质疏松症发病率和骨丢失率较高的异常现象。提示对于女性小于50岁和男性小于60岁，应加强普及骨质疏松预防知识，50岁以上的女性和60岁以上的男性还应同时采取相应干预措施，以减少骨质疏松症的发生，同时该调查为贵阳地区骨质疏松症的诊治提供了参考依据。

Bone mineral density in an adult population with osteoporosis from Guiyang area

BACKGROUND: Investigation regarding bone mineral density (BMD) change rule and osteoporosis in many areas of China has been much reported. However, studies regarding BMD change rule and osteoporosis in Guiyang area, China have been rarely reported. OBJECTIVE: To investigate BMD in adult population in Guiyang area, China and provide the basis for prevention, diagnosis and treatment of osteoporosis. METHODS: BMD was measured in 1 334 cases aged 20-79 years from Guiyang area using dual-energy X-ray absorptiometry during 2008-2011. The measurement sites included lumbar vertebrae 1 to 4 lumbar spine, right proximal femur. The peak BMD reduced by 2.0 SD was taken as the diagnosis for osteoporosis. Statistical analysis was performed based on 10-year age group according to gender. RESULTS AND CONCLUSION: The peak BMDs of 60 men and 50 women from Guiyang area appeared in age group of 20-29. Female population aged 20-29 years showed a high incidence of osteoporosis and bone loss. These findings suggest that awareness of osteoporosis prevention should be enhanced for women before 50 years old and men before 60 years old, while for the subsequent years, relevant interventions should be taken to reduce osteoporosis incidence.