脊髓灰质炎后综合征临床及电生理研究

目的研究脊髓灰质炎后综合征的临床表现和电生理特点,探讨其诊断、鉴别诊断及诊疗方法。方法回顾性分析10例脊髓灰质炎后综合征患者的临床资料。结果 10例患者受累肢体肌力均有减弱,5例伴易疲劳,3例伴寒冷不耐受,5例伴肢体疼痛。典型电生理表现为运动单位电位时限增宽、波幅增高、募集相减少;运动及感觉神经传导均正常。结论脊髓灰质炎后综合征最常见表现为无力、慢性疲劳、疼痛,诊断主要依赖于病史、临床表现、电生理等相结合的综合分析,治疗主要为康复及药物治疗,早期干预可改善患者生活质量。

Clinical and electrophysiological features of post-poliomyelitis syndrome

Objective To investigate the clinical and electrophysiological features of post-poliomyelitis syndrome (PPS), and to investigate diagnosis, differential diagnosis, and treatment.Methods The clinical data of 10 patients with PPS were analyzed retrospectively.Results All the 10 patients had weakened muscle strength in the affected limbs; 5 patients were accompanied by fatigue, 3 patients by intolerable chill, and 5 patients by pain in limbs. The typical electrophysiological features included prolonged duration, increased amplitude, and reduced recruitment order of motor unit potential, as well as normal motor and sensory nerve conduction.Objective The most common symptoms of PPS are weakness, chronic fatigue, and pain, and its diagnosis is mainly based on a comprehensive analysis of medical history, clinical manifestations, and electrophysiological features. The treatment of PPS includes rehabilitation and medication, and early intervention can improve quality of life.